ANLN-DGKB Fusion FISH Probe
The ANLN-DGKB Fusion FISH Probe is used to confirm a fusion of the ANLN and DGKB genes. The fusion of the ANLN and DGKB genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ANLN-DGKB-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ANLN-DGKB-20-RERE | 20 (40 μL) | 200 μL |
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| ANLN-DGKB-20-REOR | 20 (40 μL) | 200 μL |
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| ANLN-DGKB-20-REGO | 20 (40 μL) | 200 μL |
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| ANLN-DGKB-20-REGR | 20 (40 μL) | 200 μL |
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| ANLN-DGKB-20-REAQ | 20 (40 μL) | 200 μL |
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| ANLN-DGKB-20-ORRE | 20 (40 μL) | 200 μL |
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| ANLN-DGKB-20-OROR | 20 (40 μL) | 200 μL |
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| ANLN-DGKB-20-ORGO | 20 (40 μL) | 200 μL |
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| ANLN-DGKB-20-ORAQ | 20 (40 μL) | 200 μL |
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| ANLN-DGKB-20-GORE | 20 (40 μL) | 200 μL |
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| ANLN-DGKB-20-GOOR | 20 (40 μL) | 200 μL |
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| ANLN-DGKB-20-GOGO | 20 (40 μL) | 200 μL |
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| ANLN-DGKB-20-GOGR | 20 (40 μL) | 200 μL |
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| ANLN-DGKB-20-GOAQ | 20 (40 μL) | 200 μL |
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| ANLN-DGKB-20-GRRE | 20 (40 μL) | 200 μL |
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| ANLN-DGKB-20-GROR | 20 (40 μL) | 200 μL |
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| ANLN-DGKB-20-GRGO | 20 (40 μL) | 200 μL |
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| ANLN-DGKB-20-GRGR | 20 (40 μL) | 200 μL |
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| ANLN-DGKB-20-GRAQ | 20 (40 μL) | 200 μL |
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| ANLN-DGKB-20-AQRE | 20 (40 μL) | 200 μL |
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| ANLN-DGKB-20-AQOR | 20 (40 μL) | 200 μL |
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| ANLN-DGKB-20-AQGO | 20 (40 μL) | 200 μL |
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| ANLN-DGKB-20-AQGR | 20 (40 μL) | 200 μL |
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| ANLN-DGKB-20-AQAQ | 20 (40 μL) | 200 μL |
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DGKB Gene Summary
Diacylglycerol kinases (DGKs) are regulators of the intracellular concentration of the second messenger diacylglycerol (DAG) and thus play a key role in cellular processes. Nine mammalian isotypes have been identified, which are encoded by separate genes. Mammalian DGK isozymes contain a conserved catalytic (kinase) domain and a cysteine-rich domain (CRD). The protein encoded by this gene is a diacylglycerol kinase, beta isotype. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2017]
Gene Name: Diacylglycerol Kinase Beta
Chromosome: CHR7: 14184673 -14881075
Locus: 7p21.2
ANLN Gene Summary
This gene encodes an actin-binding protein that plays a role in cell growth and migration, and in cytokinesis. The encoded protein is thought to regulate actin cytoskeletal dynamics in podocytes, components of the glomerulus. Mutations in this gene are associated with focal segmental glomerulosclerosis 8. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014]
Gene Name: Anillin Actin Binding Protein
Chromosome: CHR7: 36429431 -36493400
Locus: 7p14.2
Gene Diseases
The ANLN DGKB Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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