ANKRD17-WDFY3 Fusion FISH Probe
The ANKRD17-WDFY3 Fusion FISH Probe is used to confirm a fusion of the ANKRD17 and WDFY3 genes. The fusion of the ANKRD17 and WDFY3 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ANKRD17-WDFY3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ANKRD17-WDFY3-20-RERE | 20 (40 μL) | 200 μL |
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| ANKRD17-WDFY3-20-REOR | 20 (40 μL) | 200 μL |
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| ANKRD17-WDFY3-20-REGO | 20 (40 μL) | 200 μL |
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| ANKRD17-WDFY3-20-REGR | 20 (40 μL) | 200 μL |
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| ANKRD17-WDFY3-20-REAQ | 20 (40 μL) | 200 μL |
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| ANKRD17-WDFY3-20-ORRE | 20 (40 μL) | 200 μL |
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| ANKRD17-WDFY3-20-OROR | 20 (40 μL) | 200 μL |
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| ANKRD17-WDFY3-20-ORGO | 20 (40 μL) | 200 μL |
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| ANKRD17-WDFY3-20-ORAQ | 20 (40 μL) | 200 μL |
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| ANKRD17-WDFY3-20-GORE | 20 (40 μL) | 200 μL |
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| ANKRD17-WDFY3-20-GOOR | 20 (40 μL) | 200 μL |
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| ANKRD17-WDFY3-20-GOGO | 20 (40 μL) | 200 μL |
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| ANKRD17-WDFY3-20-GOGR | 20 (40 μL) | 200 μL |
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| ANKRD17-WDFY3-20-GOAQ | 20 (40 μL) | 200 μL |
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| ANKRD17-WDFY3-20-GRRE | 20 (40 μL) | 200 μL |
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| ANKRD17-WDFY3-20-GROR | 20 (40 μL) | 200 μL |
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| ANKRD17-WDFY3-20-GRGO | 20 (40 μL) | 200 μL |
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| ANKRD17-WDFY3-20-GRGR | 20 (40 μL) | 200 μL |
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| ANKRD17-WDFY3-20-GRAQ | 20 (40 μL) | 200 μL |
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| ANKRD17-WDFY3-20-AQRE | 20 (40 μL) | 200 μL |
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| ANKRD17-WDFY3-20-AQOR | 20 (40 μL) | 200 μL |
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| ANKRD17-WDFY3-20-AQGO | 20 (40 μL) | 200 μL |
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| ANKRD17-WDFY3-20-AQGR | 20 (40 μL) | 200 μL |
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| ANKRD17-WDFY3-20-AQAQ | 20 (40 μL) | 200 μL |
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WDFY3 Gene Summary
This gene encodes a phosphatidylinositol 3-phosphate-binding protein that functions as a master conductor for aggregate clearance by autophagy. This protein shuttles from the nuclear membrane to colocalize with aggregated proteins, where it complexes with other autophagic components to achieve macroautophagy-mediated clearance of these aggregated proteins. However, it is not necessary for starvation-induced macroautophagy. [provided by RefSeq, May 2010]
Gene Name: WD Repeat And FYVE Domain Containing 3
Chromosome: CHR4: 85590692 -85887544
Locus: 4q21.23
ANKRD17 Gene Summary
The protein encoded by this gene belongs to the family of ankyrin repeat-containing proteins, and contains two distinct arrays of ankyrin repeats in its amino-terminal region, one with 15 ankyrin repeats, and the other with 10 ankyrin repeats. It also contains a nuclear export signal, nuclear localization signal, and a cyclin-binding RXL motif. Localization of this protein to the nucleus has been shown experimentally, and interactions between this protein and cyclin-dependent kinase 2 have been observed. It has been suggested that this protein plays a role in both DNA replication and in both anti-viral and anti-bacterial innate immune pathways. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
Gene Name: Ankyrin Repeat Domain 17
Chromosome: CHR4: 73940501 -74124502
Locus: 4q13.3
Gene Diseases
The ANKRD17 WDFY3 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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