ANKRD11-SPIRE2 Fusion FISH Probe
The ANKRD11-SPIRE2 Fusion FISH Probe is used to confirm a fusion of the ANKRD11 and SPIRE2 genes. The fusion of the ANKRD11 and SPIRE2 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ANKRD11-SPIRE2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ANKRD11-SPIRE2-20-RERE | 20 (40 μL) | 200 μL |
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| ANKRD11-SPIRE2-20-REOR | 20 (40 μL) | 200 μL |
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| ANKRD11-SPIRE2-20-REGO | 20 (40 μL) | 200 μL |
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| ANKRD11-SPIRE2-20-REGR | 20 (40 μL) | 200 μL |
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| ANKRD11-SPIRE2-20-REAQ | 20 (40 μL) | 200 μL |
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| ANKRD11-SPIRE2-20-ORRE | 20 (40 μL) | 200 μL |
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| ANKRD11-SPIRE2-20-OROR | 20 (40 μL) | 200 μL |
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| ANKRD11-SPIRE2-20-ORGO | 20 (40 μL) | 200 μL |
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| ANKRD11-SPIRE2-20-ORAQ | 20 (40 μL) | 200 μL |
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| ANKRD11-SPIRE2-20-GORE | 20 (40 μL) | 200 μL |
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| ANKRD11-SPIRE2-20-GOOR | 20 (40 μL) | 200 μL |
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| ANKRD11-SPIRE2-20-GOGO | 20 (40 μL) | 200 μL |
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| ANKRD11-SPIRE2-20-GOGR | 20 (40 μL) | 200 μL |
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| ANKRD11-SPIRE2-20-GOAQ | 20 (40 μL) | 200 μL |
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| ANKRD11-SPIRE2-20-GRRE | 20 (40 μL) | 200 μL |
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| ANKRD11-SPIRE2-20-GROR | 20 (40 μL) | 200 μL |
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| ANKRD11-SPIRE2-20-GRGO | 20 (40 μL) | 200 μL |
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| ANKRD11-SPIRE2-20-GRGR | 20 (40 μL) | 200 μL |
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| ANKRD11-SPIRE2-20-GRAQ | 20 (40 μL) | 200 μL |
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| ANKRD11-SPIRE2-20-AQRE | 20 (40 μL) | 200 μL |
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| ANKRD11-SPIRE2-20-AQOR | 20 (40 μL) | 200 μL |
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| ANKRD11-SPIRE2-20-AQGO | 20 (40 μL) | 200 μL |
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| ANKRD11-SPIRE2-20-AQGR | 20 (40 μL) | 200 μL |
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| ANKRD11-SPIRE2-20-AQAQ | 20 (40 μL) | 200 μL |
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ANKRD11 Gene Summary
This locus encodes an ankryin repeat domain-containing protein. The encoded protein inhibits ligand-dependent activation of transcription. Mutations in this gene have been associated with KBG syndrome, which is characterized by macrodontia, distinctive craniofacial features, short stature, skeletal anomalies, global developmental delay, seizures and intellectual disability. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 2 and X. [provided by RefSeq, Jan 2012]
Gene Name: Ankyrin Repeat Domain 11
Chromosome: CHR16: 89334034 -89556969
Locus: 16q24.3
SPIRE2 Gene Summary
The Spire Type Actin Nucleation Factor 2 (SPIRE2) gene is located on chr16 :89894906-89937727 at 16q24.3.
Gene Name: Spire Type Actin Nucleation Factor 2
Chromosome: CHR16: 89894906 -89937727
Locus: 16q24.3
Gene Diseases
The ANKRD11 SPIRE2 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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