ANKRD11-DPEP1 Fusion FISH Probe
The ANKRD11-DPEP1 Fusion FISH Probe is used to confirm a fusion of the ANKRD11 and DPEP1 genes. The fusion of the ANKRD11 and DPEP1 genes has been associated with Thyroid Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ANKRD11-DPEP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ANKRD11-DPEP1-20-RERE | 20 (40 μL) | 200 μL |
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| ANKRD11-DPEP1-20-REOR | 20 (40 μL) | 200 μL |
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| ANKRD11-DPEP1-20-REGO | 20 (40 μL) | 200 μL |
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| ANKRD11-DPEP1-20-REGR | 20 (40 μL) | 200 μL |
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| ANKRD11-DPEP1-20-REAQ | 20 (40 μL) | 200 μL |
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| ANKRD11-DPEP1-20-ORRE | 20 (40 μL) | 200 μL |
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| ANKRD11-DPEP1-20-OROR | 20 (40 μL) | 200 μL |
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| ANKRD11-DPEP1-20-ORGO | 20 (40 μL) | 200 μL |
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| ANKRD11-DPEP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ANKRD11-DPEP1-20-GORE | 20 (40 μL) | 200 μL |
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| ANKRD11-DPEP1-20-GOOR | 20 (40 μL) | 200 μL |
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| ANKRD11-DPEP1-20-GOGO | 20 (40 μL) | 200 μL |
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| ANKRD11-DPEP1-20-GOGR | 20 (40 μL) | 200 μL |
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| ANKRD11-DPEP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ANKRD11-DPEP1-20-GRRE | 20 (40 μL) | 200 μL |
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| ANKRD11-DPEP1-20-GROR | 20 (40 μL) | 200 μL |
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| ANKRD11-DPEP1-20-GRGO | 20 (40 μL) | 200 μL |
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| ANKRD11-DPEP1-20-GRGR | 20 (40 μL) | 200 μL |
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| ANKRD11-DPEP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ANKRD11-DPEP1-20-AQRE | 20 (40 μL) | 200 μL |
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| ANKRD11-DPEP1-20-AQOR | 20 (40 μL) | 200 μL |
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| ANKRD11-DPEP1-20-AQGO | 20 (40 μL) | 200 μL |
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| ANKRD11-DPEP1-20-AQGR | 20 (40 μL) | 200 μL |
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| ANKRD11-DPEP1-20-AQAQ | 20 (40 μL) | 200 μL |
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DPEP1 Gene Summary
The protein encoded by this gene is a kidney membrane enzyme involved in the metabolism of glutathione and other similar proteins by dipeptide hydrolysis. The encoded protein is known to regulate leukotriene activity by catalyzing the conversion of leukotriene D4 to leukotriene E4. This protein uses zinc as a cofactor and acts as a disulfide-linked homodimer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jan 2012]
Gene Name: Dipeptidase 1
Chromosome: CHR16: 89679715 -89704839
Locus: 16q24.3
ANKRD11 Gene Summary
This locus encodes an ankryin repeat domain-containing protein. The encoded protein inhibits ligand-dependent activation of transcription. Mutations in this gene have been associated with KBG syndrome, which is characterized by macrodontia, distinctive craniofacial features, short stature, skeletal anomalies, global developmental delay, seizures and intellectual disability. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 2 and X. [provided by RefSeq, Jan 2012]
Gene Name: Ankyrin Repeat Domain 11
Chromosome: CHR16: 89334034 -89556969
Locus: 16q24.3
Gene Diseases
The ANKRD11 DPEP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Thyroid Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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