ANKRD11-BRMS1 Fusion FISH Probe
The ANKRD11-BRMS1 Fusion FISH Probe is used to confirm a fusion of the ANKRD11 and BRMS1 genes. The fusion of the ANKRD11 and BRMS1 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ANKRD11-BRMS1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ANKRD11-BRMS1-20-RERE | 20 (40 μL) | 200 μL |
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| ANKRD11-BRMS1-20-REOR | 20 (40 μL) | 200 μL |
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| ANKRD11-BRMS1-20-REGO | 20 (40 μL) | 200 μL |
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| ANKRD11-BRMS1-20-REGR | 20 (40 μL) | 200 μL |
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| ANKRD11-BRMS1-20-REAQ | 20 (40 μL) | 200 μL |
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| ANKRD11-BRMS1-20-ORRE | 20 (40 μL) | 200 μL |
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| ANKRD11-BRMS1-20-OROR | 20 (40 μL) | 200 μL |
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| ANKRD11-BRMS1-20-ORGO | 20 (40 μL) | 200 μL |
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| ANKRD11-BRMS1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ANKRD11-BRMS1-20-GORE | 20 (40 μL) | 200 μL |
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| ANKRD11-BRMS1-20-GOOR | 20 (40 μL) | 200 μL |
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| ANKRD11-BRMS1-20-GOGO | 20 (40 μL) | 200 μL |
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| ANKRD11-BRMS1-20-GOGR | 20 (40 μL) | 200 μL |
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| ANKRD11-BRMS1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ANKRD11-BRMS1-20-GRRE | 20 (40 μL) | 200 μL |
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| ANKRD11-BRMS1-20-GROR | 20 (40 μL) | 200 μL |
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| ANKRD11-BRMS1-20-GRGO | 20 (40 μL) | 200 μL |
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| ANKRD11-BRMS1-20-GRGR | 20 (40 μL) | 200 μL |
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| ANKRD11-BRMS1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ANKRD11-BRMS1-20-AQRE | 20 (40 μL) | 200 μL |
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| ANKRD11-BRMS1-20-AQOR | 20 (40 μL) | 200 μL |
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| ANKRD11-BRMS1-20-AQGO | 20 (40 μL) | 200 μL |
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| ANKRD11-BRMS1-20-AQGR | 20 (40 μL) | 200 μL |
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| ANKRD11-BRMS1-20-AQAQ | 20 (40 μL) | 200 μL |
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BRMS1 Gene Summary
This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Name: Breast Cancer Metastasis Suppressor 1
Chromosome: CHR11: 66104803 -66112582
Locus: 11q13.2
ANKRD11 Gene Summary
This locus encodes an ankryin repeat domain-containing protein. The encoded protein inhibits ligand-dependent activation of transcription. Mutations in this gene have been associated with KBG syndrome, which is characterized by macrodontia, distinctive craniofacial features, short stature, skeletal anomalies, global developmental delay, seizures and intellectual disability. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 2 and X. [provided by RefSeq, Jan 2012]
Gene Name: Ankyrin Repeat Domain 11
Chromosome: CHR16: 89334034 -89556969
Locus: 16q24.3
Gene Diseases
The ANKRD11 BRMS1 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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