ANKLE2-MGAT1 Fusion FISH Probe
The ANKLE2-MGAT1 Fusion FISH Probe is used to confirm a fusion of the ANKLE2 and MGAT1 genes. The fusion of the ANKLE2 and MGAT1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ANKLE2-MGAT1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ANKLE2-MGAT1-20-RERE | 20 (40 μL) | 200 μL |
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| ANKLE2-MGAT1-20-REOR | 20 (40 μL) | 200 μL |
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| ANKLE2-MGAT1-20-REGO | 20 (40 μL) | 200 μL |
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| ANKLE2-MGAT1-20-REGR | 20 (40 μL) | 200 μL |
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| ANKLE2-MGAT1-20-REAQ | 20 (40 μL) | 200 μL |
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| ANKLE2-MGAT1-20-ORRE | 20 (40 μL) | 200 μL |
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| ANKLE2-MGAT1-20-OROR | 20 (40 μL) | 200 μL |
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| ANKLE2-MGAT1-20-ORGO | 20 (40 μL) | 200 μL |
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| ANKLE2-MGAT1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ANKLE2-MGAT1-20-GORE | 20 (40 μL) | 200 μL |
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| ANKLE2-MGAT1-20-GOOR | 20 (40 μL) | 200 μL |
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| ANKLE2-MGAT1-20-GOGO | 20 (40 μL) | 200 μL |
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| ANKLE2-MGAT1-20-GOGR | 20 (40 μL) | 200 μL |
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| ANKLE2-MGAT1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ANKLE2-MGAT1-20-GRRE | 20 (40 μL) | 200 μL |
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| ANKLE2-MGAT1-20-GROR | 20 (40 μL) | 200 μL |
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| ANKLE2-MGAT1-20-GRGO | 20 (40 μL) | 200 μL |
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| ANKLE2-MGAT1-20-GRGR | 20 (40 μL) | 200 μL |
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| ANKLE2-MGAT1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ANKLE2-MGAT1-20-AQRE | 20 (40 μL) | 200 μL |
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| ANKLE2-MGAT1-20-AQOR | 20 (40 μL) | 200 μL |
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| ANKLE2-MGAT1-20-AQGO | 20 (40 μL) | 200 μL |
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| ANKLE2-MGAT1-20-AQGR | 20 (40 μL) | 200 μL |
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| ANKLE2-MGAT1-20-AQAQ | 20 (40 μL) | 200 μL |
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MGAT1 Gene Summary
There are believed to be over 100 different glycosyltransferases involved in the synthesis of protein-bound and lipid-bound oligosaccharides. UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I is a medial-Golgi enzyme essential for the synthesis of hybrid and complex N-glycans. The protein, encoded by a single exon, shows typical features of a type II transmembrane protein. The protein is believed to be essential for normal embryogenesis. Several variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Mannosyl (alpha-1,3-)-glycoprotein Beta-1,2-N-acetylglucosaminyltransferase
Chromosome: CHR5: 180217540 -180237137
Locus: 5q35.3
ANKLE2 Gene Summary
This gene encodes a member of the LEM family of inner nuclear membrane proteins. The encoded protein functions as a mitotic regulator through postmitotic formation of the nuclear envelope. Mutations in this gene cause morphology defects in the nuclear envelope and BAF hyperphosphorylation. [provided by RefSeq, Mar 2014]
Gene Name: Ankyrin Repeat And LEM Domain Containing 2
Chromosome: CHR12: 133302253 -133338451
Locus: 12q24.33
Gene Diseases
The ANKLE2 MGAT1 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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