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ANKLE2-MGAT1 Fusion FISH Probe

The ANKLE2-MGAT1 Fusion FISH Probe is used to confirm a fusion of the ANKLE2 and MGAT1 genes. The fusion of the ANKLE2 and MGAT1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ANKLE2-MGAT1-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
ANKLE2-MGAT1-20-RERE 20 (40 μL) 200 μL
ANKLE2-MGAT1-20-REOR 20 (40 μL) 200 μL
ANKLE2-MGAT1-20-REGO 20 (40 μL) 200 μL
ANKLE2-MGAT1-20-REGR 20 (40 μL) 200 μL
ANKLE2-MGAT1-20-REAQ 20 (40 μL) 200 μL
ANKLE2-MGAT1-20-ORRE 20 (40 μL) 200 μL
ANKLE2-MGAT1-20-OROR 20 (40 μL) 200 μL
ANKLE2-MGAT1-20-ORGO 20 (40 μL) 200 μL
ANKLE2-MGAT1-20-ORAQ 20 (40 μL) 200 μL
ANKLE2-MGAT1-20-GORE 20 (40 μL) 200 μL
ANKLE2-MGAT1-20-GOOR 20 (40 μL) 200 μL
ANKLE2-MGAT1-20-GOGO 20 (40 μL) 200 μL
ANKLE2-MGAT1-20-GOGR 20 (40 μL) 200 μL
ANKLE2-MGAT1-20-GOAQ 20 (40 μL) 200 μL
ANKLE2-MGAT1-20-GRRE 20 (40 μL) 200 μL
ANKLE2-MGAT1-20-GROR 20 (40 μL) 200 μL
ANKLE2-MGAT1-20-GRGO 20 (40 μL) 200 μL
ANKLE2-MGAT1-20-GRGR 20 (40 μL) 200 μL
ANKLE2-MGAT1-20-GRAQ 20 (40 μL) 200 μL
ANKLE2-MGAT1-20-AQRE 20 (40 μL) 200 μL
ANKLE2-MGAT1-20-AQOR 20 (40 μL) 200 μL
ANKLE2-MGAT1-20-AQGO 20 (40 μL) 200 μL
ANKLE2-MGAT1-20-AQGR 20 (40 μL) 200 μL
ANKLE2-MGAT1-20-AQAQ 20 (40 μL) 200 μL

MGAT1 Gene Summary

There are believed to be over 100 different glycosyltransferases involved in the synthesis of protein-bound and lipid-bound oligosaccharides. UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I is a medial-Golgi enzyme essential for the synthesis of hybrid and complex N-glycans. The protein, encoded by a single exon, shows typical features of a type II transmembrane protein. The protein is believed to be essential for normal embryogenesis. Several variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Gene Name: Mannosyl (alpha-1,3-)-glycoprotein Beta-1,2-N-acetylglucosaminyltransferase

Chromosome: CHR5: 180217540 -180237137

Locus: 5q35.3

ANKLE2 Gene Summary

This gene encodes a member of the LEM family of inner nuclear membrane proteins. The encoded protein functions as a mitotic regulator through postmitotic formation of the nuclear envelope. Mutations in this gene cause morphology defects in the nuclear envelope and BAF hyperphosphorylation. [provided by RefSeq, Mar 2014]

Gene Name: Ankyrin Repeat And LEM Domain Containing 2

Chromosome: CHR12: 133302253 -133338451

Locus: 12q24.33

Gene Diseases

The ANKLE2 MGAT1 Fusion has been associated with the following diseases:

Disease Name
Sarcoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.