ANKIB1-CYP3A4 Fusion FISH Probe
The ANKIB1-CYP3A4 Fusion FISH Probe is used to confirm a fusion of the ANKIB1 and CYP3A4 genes. The fusion of the ANKIB1 and CYP3A4 genes has been associated with Pancreatic Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ANKIB1-CYP3A4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ANKIB1-CYP3A4-20-RERE | 20 (40 μL) | 200 μL |
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| ANKIB1-CYP3A4-20-REOR | 20 (40 μL) | 200 μL |
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| ANKIB1-CYP3A4-20-REGO | 20 (40 μL) | 200 μL |
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| ANKIB1-CYP3A4-20-REGR | 20 (40 μL) | 200 μL |
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| ANKIB1-CYP3A4-20-REAQ | 20 (40 μL) | 200 μL |
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| ANKIB1-CYP3A4-20-ORRE | 20 (40 μL) | 200 μL |
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| ANKIB1-CYP3A4-20-OROR | 20 (40 μL) | 200 μL |
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| ANKIB1-CYP3A4-20-ORGO | 20 (40 μL) | 200 μL |
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| ANKIB1-CYP3A4-20-ORAQ | 20 (40 μL) | 200 μL |
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| ANKIB1-CYP3A4-20-GORE | 20 (40 μL) | 200 μL |
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| ANKIB1-CYP3A4-20-GOOR | 20 (40 μL) | 200 μL |
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| ANKIB1-CYP3A4-20-GOGO | 20 (40 μL) | 200 μL |
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| ANKIB1-CYP3A4-20-GOGR | 20 (40 μL) | 200 μL |
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| ANKIB1-CYP3A4-20-GOAQ | 20 (40 μL) | 200 μL |
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| ANKIB1-CYP3A4-20-GRRE | 20 (40 μL) | 200 μL |
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| ANKIB1-CYP3A4-20-GROR | 20 (40 μL) | 200 μL |
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| ANKIB1-CYP3A4-20-GRGO | 20 (40 μL) | 200 μL |
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| ANKIB1-CYP3A4-20-GRGR | 20 (40 μL) | 200 μL |
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| ANKIB1-CYP3A4-20-GRAQ | 20 (40 μL) | 200 μL |
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| ANKIB1-CYP3A4-20-AQRE | 20 (40 μL) | 200 μL |
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| ANKIB1-CYP3A4-20-AQOR | 20 (40 μL) | 200 μL |
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| ANKIB1-CYP3A4-20-AQGO | 20 (40 μL) | 200 μL |
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| ANKIB1-CYP3A4-20-AQGR | 20 (40 μL) | 200 μL |
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| ANKIB1-CYP3A4-20-AQAQ | 20 (40 μL) | 200 μL |
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CYP3A4 Gene Summary
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Feb 2011]
Gene Name: Cytochrome P450 Family 3 Subfamily A Member 4
Chromosome: CHR7: 99354582 -99381811
Locus: 7q22.1
ANKIB1 Gene Summary
The Ankyrin Repeat And IBR Domain Containing 1 (ANKIB1) gene is located on chr7 :91875547-92030698 at 7q21.2.
Gene Name: Ankyrin Repeat And IBR Domain Containing 1
Chromosome: CHR7: 91875547 -92030698
Locus: 7q21.2
Gene Diseases
The ANKIB1 CYP3A4 Fusion has been associated with the following diseases:
| Disease Name |
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| Pancreatic Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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