ANKHD1-TIAM2 Fusion FISH Probe
The ANKHD1-TIAM2 Fusion FISH Probe is used to confirm a fusion of the ANKHD1 and TIAM2 genes. The fusion of the ANKHD1 and TIAM2 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ANKHD1-TIAM2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ANKHD1-TIAM2-20-RERE | 20 (40 μL) | 200 μL |
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| ANKHD1-TIAM2-20-REOR | 20 (40 μL) | 200 μL |
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| ANKHD1-TIAM2-20-REGO | 20 (40 μL) | 200 μL |
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| ANKHD1-TIAM2-20-REGR | 20 (40 μL) | 200 μL |
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| ANKHD1-TIAM2-20-REAQ | 20 (40 μL) | 200 μL |
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| ANKHD1-TIAM2-20-ORRE | 20 (40 μL) | 200 μL |
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| ANKHD1-TIAM2-20-OROR | 20 (40 μL) | 200 μL |
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| ANKHD1-TIAM2-20-ORGO | 20 (40 μL) | 200 μL |
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| ANKHD1-TIAM2-20-ORAQ | 20 (40 μL) | 200 μL |
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| ANKHD1-TIAM2-20-GORE | 20 (40 μL) | 200 μL |
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| ANKHD1-TIAM2-20-GOOR | 20 (40 μL) | 200 μL |
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| ANKHD1-TIAM2-20-GOGO | 20 (40 μL) | 200 μL |
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| ANKHD1-TIAM2-20-GOGR | 20 (40 μL) | 200 μL |
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| ANKHD1-TIAM2-20-GOAQ | 20 (40 μL) | 200 μL |
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| ANKHD1-TIAM2-20-GRRE | 20 (40 μL) | 200 μL |
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| ANKHD1-TIAM2-20-GROR | 20 (40 μL) | 200 μL |
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| ANKHD1-TIAM2-20-GRGO | 20 (40 μL) | 200 μL |
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| ANKHD1-TIAM2-20-GRGR | 20 (40 μL) | 200 μL |
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| ANKHD1-TIAM2-20-GRAQ | 20 (40 μL) | 200 μL |
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| ANKHD1-TIAM2-20-AQRE | 20 (40 μL) | 200 μL |
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| ANKHD1-TIAM2-20-AQOR | 20 (40 μL) | 200 μL |
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| ANKHD1-TIAM2-20-AQGO | 20 (40 μL) | 200 μL |
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| ANKHD1-TIAM2-20-AQGR | 20 (40 μL) | 200 μL |
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| ANKHD1-TIAM2-20-AQAQ | 20 (40 μL) | 200 μL |
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TIAM2 Gene Summary
This gene encodes a guanine nucleotide exchange factor. A highly similar mouse protein specifically activates ras-related C3 botulinum substrate 1, converting this Rho-like guanosine triphosphatase (GTPase) from a guanosine diphosphate-bound inactive state to a guanosine triphosphate-bound active state. The encoded protein may play a role in neural cell development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Gene Name: T-cell Lymphoma Invasion And Metastasis 2
Chromosome: CHR6: 155411422 -155578857
Locus: 6q25.2-q25.3
ANKHD1 Gene Summary
This gene encodes a protein with multiple ankyrin repeat domains and a single KH-domain. The protein is thought to function as a scaffolding protein, and it may be involved in the regulation of caspases and thereby play an antiapoptotic role in cell survival. Alternative splicing results in multiple transcript variants, one of which generates a fusion transcript (MASK-BP3) with the downstream eIF4E-binding protein 3 (EIF4EBP3) gene, resulting in a protein comprised of the ANKHD1 sequence for the majority of the protein and a different C-terminus due to an alternate reading frame for the EIF4EBP3 segments. [provided by RefSeq, Sep 2010]
Gene Name: Ankyrin Repeat And KH Domain Containing 1
Chromosome: CHR5: 139781398 -139919441
Locus: 5q31.3
Gene Diseases
The ANKHD1 TIAM2 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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