ANKH-STEAP3 Fusion FISH Probe
The ANKH-STEAP3 Fusion FISH Probe is used to confirm a fusion of the ANKH and STEAP3 genes. The fusion of the ANKH and STEAP3 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ANKH-STEAP3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ANKH-STEAP3-20-RERE | 20 (40 μL) | 200 μL |
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| ANKH-STEAP3-20-REOR | 20 (40 μL) | 200 μL |
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| ANKH-STEAP3-20-REGO | 20 (40 μL) | 200 μL |
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| ANKH-STEAP3-20-REGR | 20 (40 μL) | 200 μL |
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| ANKH-STEAP3-20-REAQ | 20 (40 μL) | 200 μL |
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| ANKH-STEAP3-20-ORRE | 20 (40 μL) | 200 μL |
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| ANKH-STEAP3-20-OROR | 20 (40 μL) | 200 μL |
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| ANKH-STEAP3-20-ORGO | 20 (40 μL) | 200 μL |
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| ANKH-STEAP3-20-ORAQ | 20 (40 μL) | 200 μL |
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| ANKH-STEAP3-20-GORE | 20 (40 μL) | 200 μL |
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| ANKH-STEAP3-20-GOOR | 20 (40 μL) | 200 μL |
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| ANKH-STEAP3-20-GOGO | 20 (40 μL) | 200 μL |
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| ANKH-STEAP3-20-GOGR | 20 (40 μL) | 200 μL |
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| ANKH-STEAP3-20-GOAQ | 20 (40 μL) | 200 μL |
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| ANKH-STEAP3-20-GRRE | 20 (40 μL) | 200 μL |
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| ANKH-STEAP3-20-GROR | 20 (40 μL) | 200 μL |
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| ANKH-STEAP3-20-GRGO | 20 (40 μL) | 200 μL |
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| ANKH-STEAP3-20-GRGR | 20 (40 μL) | 200 μL |
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| ANKH-STEAP3-20-GRAQ | 20 (40 μL) | 200 μL |
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| ANKH-STEAP3-20-AQRE | 20 (40 μL) | 200 μL |
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| ANKH-STEAP3-20-AQOR | 20 (40 μL) | 200 μL |
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| ANKH-STEAP3-20-AQGO | 20 (40 μL) | 200 μL |
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| ANKH-STEAP3-20-AQGR | 20 (40 μL) | 200 μL |
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| ANKH-STEAP3-20-AQAQ | 20 (40 μL) | 200 μL |
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STEAP3 Gene Summary
This gene encodes a multipass membrane protein that functions as an iron transporter. The encoded protein can reduce both iron (Fe3+) and copper (Cu2+) cations. This protein may mediate downstream responses to p53, including promoting apoptosis. Deficiency in this gene can cause anemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]
Gene Name: STEAP3 Metalloreductase
Chromosome: CHR2: 119981383 -120023227
Locus: 2q14.2
ANKH Gene Summary
This gene encodes a multipass transmembrane protein that is expressed in joints and other tissues and controls pyrophosphate levels in cultured cells. Progressive ankylosis-mediated control of pyrophosphate levels has been suggested as a possible mechanism regulating tissue calcification and susceptibility to arthritis in higher animals. Mutations in this gene have been associated with autosomal dominant craniometaphyseal dysplasia. [provided by RefSeq, Jul 2008]
Gene Name: ANKH Inorganic Pyrophosphate Transport Regulator
Chromosome: CHR5: 14704908 -14871887
Locus: 5p15.2
Gene Diseases
The ANKH STEAP3 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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