ANKH-ANO6 Fusion FISH Probe
The ANKH-ANO6 Fusion FISH Probe is used to confirm a fusion of the ANKH and ANO6 genes. The fusion of the ANKH and ANO6 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ANKH-ANO6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ANKH-ANO6-20-RERE | 20 (40 μL) | 200 μL |
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| ANKH-ANO6-20-REOR | 20 (40 μL) | 200 μL |
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| ANKH-ANO6-20-REGO | 20 (40 μL) | 200 μL |
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| ANKH-ANO6-20-REGR | 20 (40 μL) | 200 μL |
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| ANKH-ANO6-20-REAQ | 20 (40 μL) | 200 μL |
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| ANKH-ANO6-20-ORRE | 20 (40 μL) | 200 μL |
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| ANKH-ANO6-20-OROR | 20 (40 μL) | 200 μL |
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| ANKH-ANO6-20-ORGO | 20 (40 μL) | 200 μL |
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| ANKH-ANO6-20-ORAQ | 20 (40 μL) | 200 μL |
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| ANKH-ANO6-20-GORE | 20 (40 μL) | 200 μL |
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| ANKH-ANO6-20-GOOR | 20 (40 μL) | 200 μL |
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| ANKH-ANO6-20-GOGO | 20 (40 μL) | 200 μL |
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| ANKH-ANO6-20-GOGR | 20 (40 μL) | 200 μL |
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| ANKH-ANO6-20-GOAQ | 20 (40 μL) | 200 μL |
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| ANKH-ANO6-20-GRRE | 20 (40 μL) | 200 μL |
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| ANKH-ANO6-20-GROR | 20 (40 μL) | 200 μL |
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| ANKH-ANO6-20-GRGO | 20 (40 μL) | 200 μL |
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| ANKH-ANO6-20-GRGR | 20 (40 μL) | 200 μL |
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| ANKH-ANO6-20-GRAQ | 20 (40 μL) | 200 μL |
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| ANKH-ANO6-20-AQRE | 20 (40 μL) | 200 μL |
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| ANKH-ANO6-20-AQOR | 20 (40 μL) | 200 μL |
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| ANKH-ANO6-20-AQGO | 20 (40 μL) | 200 μL |
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| ANKH-ANO6-20-AQGR | 20 (40 μL) | 200 μL |
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| ANKH-ANO6-20-AQAQ | 20 (40 μL) | 200 μL |
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ANKH Gene Summary
This gene encodes a multipass transmembrane protein that is expressed in joints and other tissues and controls pyrophosphate levels in cultured cells. Progressive ankylosis-mediated control of pyrophosphate levels has been suggested as a possible mechanism regulating tissue calcification and susceptibility to arthritis in higher animals. Mutations in this gene have been associated with autosomal dominant craniometaphyseal dysplasia. [provided by RefSeq, Jul 2008]
Gene Name: ANKH Inorganic Pyrophosphate Transport Regulator
Chromosome: CHR5: 14704908 -14871887
Locus: 5p15.2
ANO6 Gene Summary
This gene encodes a multi-pass transmembrane protein that belongs to the anoctamin family. This protein is an essential component for the calcium-dependent exposure of phosphatidylserine on the cell surface. The scrambling of phospholipid occurs in various biological systems, such as when blood platelets are activated, they expose phosphatidylserine to trigger the clotting system. Mutations in this gene are associated with Scott syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2011]
Gene Name: Anoctamin 6
Chromosome: CHR12: 45609769 -45834187
Locus: 12q12
Gene Diseases
The ANKH ANO6 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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