ANKFY1-CCDC88C Fusion FISH Probe
The ANKFY1-CCDC88C Fusion FISH Probe is used to confirm a fusion of the ANKFY1 and CCDC88C genes. The fusion of the ANKFY1 and CCDC88C genes has been associated with Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ANKFY1-CCDC88C-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ANKFY1-CCDC88C-20-RERE | 20 (40 μL) | 200 μL |
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| ANKFY1-CCDC88C-20-REOR | 20 (40 μL) | 200 μL |
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| ANKFY1-CCDC88C-20-REGO | 20 (40 μL) | 200 μL |
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| ANKFY1-CCDC88C-20-REGR | 20 (40 μL) | 200 μL |
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| ANKFY1-CCDC88C-20-REAQ | 20 (40 μL) | 200 μL |
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| ANKFY1-CCDC88C-20-ORRE | 20 (40 μL) | 200 μL |
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| ANKFY1-CCDC88C-20-OROR | 20 (40 μL) | 200 μL |
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| ANKFY1-CCDC88C-20-ORGO | 20 (40 μL) | 200 μL |
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| ANKFY1-CCDC88C-20-ORAQ | 20 (40 μL) | 200 μL |
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| ANKFY1-CCDC88C-20-GORE | 20 (40 μL) | 200 μL |
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| ANKFY1-CCDC88C-20-GOOR | 20 (40 μL) | 200 μL |
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| ANKFY1-CCDC88C-20-GOGO | 20 (40 μL) | 200 μL |
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| ANKFY1-CCDC88C-20-GOGR | 20 (40 μL) | 200 μL |
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| ANKFY1-CCDC88C-20-GOAQ | 20 (40 μL) | 200 μL |
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| ANKFY1-CCDC88C-20-GRRE | 20 (40 μL) | 200 μL |
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| ANKFY1-CCDC88C-20-GROR | 20 (40 μL) | 200 μL |
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| ANKFY1-CCDC88C-20-GRGO | 20 (40 μL) | 200 μL |
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| ANKFY1-CCDC88C-20-GRGR | 20 (40 μL) | 200 μL |
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| ANKFY1-CCDC88C-20-GRAQ | 20 (40 μL) | 200 μL |
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| ANKFY1-CCDC88C-20-AQRE | 20 (40 μL) | 200 μL |
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| ANKFY1-CCDC88C-20-AQOR | 20 (40 μL) | 200 μL |
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| ANKFY1-CCDC88C-20-AQGO | 20 (40 μL) | 200 μL |
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| ANKFY1-CCDC88C-20-AQGR | 20 (40 μL) | 200 μL |
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| ANKFY1-CCDC88C-20-AQAQ | 20 (40 μL) | 200 μL |
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ANKFY1 Gene Summary
This gene encodes a cytoplasmic protein that contains a coiled-coil structure and a BTB/POZ domain at its N-terminus, ankyrin repeats in the middle portion, and a FYVE-finger motif at its C-terminus. This protein belongs to a subgroup of double zinc finger proteins which may be involved in vesicle or protein transport. Alternate splicing results in multiple transcript variants of this gene. [provided by RefSeq, Apr 2012]
Gene Name: Ankyrin Repeat And FYVE Domain Containing 1
Chromosome: CHR17: 4066664 -4167274
Locus: 17p13.2
CCDC88C Gene Summary
This gene encodes a ubiquitously expressed coiled-coil domain-containing protein that interacts with the dishevelled protein and is a negative regulator of the Wnt signalling pathway. The protein encoded by this gene has a PDZ-domain binding motif in its C-terminus with which it interacts with the dishevelled protein. Dishevelled is a scaffold protein involved in the regulation of the Wnt signaling pathway. The Wnt signaling pathway plays an important role in embryonic development, tissue maintenance, and cancer progression. Mutations in this gene cause autosomal recessive, primary non-syndromic congenital hydrocephalus; a condition characterized by excessive accumulation of cerebrospinal fluid in the ventricles of the brain. [provided by RefSeq, Jan 2013]
Gene Name: Coiled-coil Domain Containing 88C
Chromosome: CHR14: 91737666 -91884188
Locus: 14q32.11-q32.12
Gene Diseases
The ANKFY1 CCDC88C Fusion has been associated with the following diseases:
| Disease Name |
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| Esophageal Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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