ANK3-WDFY4 Fusion FISH Probe
The ANK3-WDFY4 Fusion FISH Probe is used to confirm a fusion of the ANK3 and WDFY4 genes. The fusion of the ANK3 and WDFY4 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ANK3-WDFY4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ANK3-WDFY4-20-RERE | 20 (40 μL) | 200 μL |
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| ANK3-WDFY4-20-REOR | 20 (40 μL) | 200 μL |
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| ANK3-WDFY4-20-REGO | 20 (40 μL) | 200 μL |
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| ANK3-WDFY4-20-REGR | 20 (40 μL) | 200 μL |
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| ANK3-WDFY4-20-REAQ | 20 (40 μL) | 200 μL |
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| ANK3-WDFY4-20-ORRE | 20 (40 μL) | 200 μL |
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| ANK3-WDFY4-20-OROR | 20 (40 μL) | 200 μL |
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| ANK3-WDFY4-20-ORGO | 20 (40 μL) | 200 μL |
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| ANK3-WDFY4-20-ORAQ | 20 (40 μL) | 200 μL |
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| ANK3-WDFY4-20-GORE | 20 (40 μL) | 200 μL |
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| ANK3-WDFY4-20-GOOR | 20 (40 μL) | 200 μL |
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| ANK3-WDFY4-20-GOGO | 20 (40 μL) | 200 μL |
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| ANK3-WDFY4-20-GOGR | 20 (40 μL) | 200 μL |
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| ANK3-WDFY4-20-GOAQ | 20 (40 μL) | 200 μL |
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| ANK3-WDFY4-20-GRRE | 20 (40 μL) | 200 μL |
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| ANK3-WDFY4-20-GROR | 20 (40 μL) | 200 μL |
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| ANK3-WDFY4-20-GRGO | 20 (40 μL) | 200 μL |
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| ANK3-WDFY4-20-GRGR | 20 (40 μL) | 200 μL |
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| ANK3-WDFY4-20-GRAQ | 20 (40 μL) | 200 μL |
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| ANK3-WDFY4-20-AQRE | 20 (40 μL) | 200 μL |
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| ANK3-WDFY4-20-AQOR | 20 (40 μL) | 200 μL |
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| ANK3-WDFY4-20-AQGO | 20 (40 μL) | 200 μL |
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| ANK3-WDFY4-20-AQGR | 20 (40 μL) | 200 μL |
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| ANK3-WDFY4-20-AQAQ | 20 (40 μL) | 200 μL |
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ANK3 Gene Summary
Ankyrins are a family of proteins that are believed to link the integral membrane proteins to the underlying spectrin-actin cytoskeleton and play key roles in activities such as cell motility, activation, proliferation, contact, and the maintenance of specialized membrane domains. Multiple isoforms of ankyrin with different affinities for various target proteins are expressed in a tissue-specific, developmentally regulated manner. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats; a central region with a highly conserved spectrin binding domain; and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. Ankyrin 3 is an immunologically distinct gene product from ankyrins 1 and 2, and was originally found at the axonal initial segment and nodes of Ranvier of neurons in the central and peripheral nervous systems. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011]
Gene Name: Ankyrin 3
Chromosome: CHR10: 61786055 -62493284
Locus: 10q21.2
WDFY4 Gene Summary
The WDFY Family Member 4 (WDFY4) gene is located on chr10 :49893517-50191001 at 10q11.23.
Gene Name: WDFY Family Member 4
Chromosome: CHR10: 49893517 -50191001
Locus: 10q11.23
Gene Diseases
The ANK3 WDFY4 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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