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ANK2-ARHGAP10 Fusion FISH Probe

The ANK2-ARHGAP10 Fusion FISH Probe is used to confirm a fusion of the ANK2 and ARHGAP10 genes. The fusion of the ANK2 and ARHGAP10 genes has been associated with Glioblastoma Multiforme. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ANK2-ARHGAP10-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
ANK2-ARHGAP10-20-RERE 20 (40 μL) 200 μL
ANK2-ARHGAP10-20-REOR 20 (40 μL) 200 μL
ANK2-ARHGAP10-20-REGO 20 (40 μL) 200 μL
ANK2-ARHGAP10-20-REGR 20 (40 μL) 200 μL
ANK2-ARHGAP10-20-REAQ 20 (40 μL) 200 μL
ANK2-ARHGAP10-20-ORRE 20 (40 μL) 200 μL
ANK2-ARHGAP10-20-OROR 20 (40 μL) 200 μL
ANK2-ARHGAP10-20-ORGO 20 (40 μL) 200 μL
ANK2-ARHGAP10-20-ORAQ 20 (40 μL) 200 μL
ANK2-ARHGAP10-20-GORE 20 (40 μL) 200 μL
ANK2-ARHGAP10-20-GOOR 20 (40 μL) 200 μL
ANK2-ARHGAP10-20-GOGO 20 (40 μL) 200 μL
ANK2-ARHGAP10-20-GOGR 20 (40 μL) 200 μL
ANK2-ARHGAP10-20-GOAQ 20 (40 μL) 200 μL
ANK2-ARHGAP10-20-GRRE 20 (40 μL) 200 μL
ANK2-ARHGAP10-20-GROR 20 (40 μL) 200 μL
ANK2-ARHGAP10-20-GRGO 20 (40 μL) 200 μL
ANK2-ARHGAP10-20-GRGR 20 (40 μL) 200 μL
ANK2-ARHGAP10-20-GRAQ 20 (40 μL) 200 μL
ANK2-ARHGAP10-20-AQRE 20 (40 μL) 200 μL
ANK2-ARHGAP10-20-AQOR 20 (40 μL) 200 μL
ANK2-ARHGAP10-20-AQGO 20 (40 μL) 200 μL
ANK2-ARHGAP10-20-AQGR 20 (40 μL) 200 μL
ANK2-ARHGAP10-20-AQAQ 20 (40 μL) 200 μL

ANK2 Gene Summary

This gene encodes a member of the ankyrin family of proteins that link the integral membrane proteins to the underlying spectrin-actin cytoskeleton. Ankyrins play key roles in activities such as cell motility, activation, proliferation, contact and the maintenance of specialized membrane domains. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats; a central region with a highly conserved spectrin binding domain; and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. The protein encoded by this gene is required for targeting and stability of Na/Ca exchanger 1 in cardiomyocytes. Mutations in this gene cause long QT syndrome 4 and cardiac arrhythmia syndrome. Multiple transcript variants encoding different isoforms have been described. [provided by RefSeq, Dec 2011]

Gene Name: Ankyrin 2

Chromosome: CHR4: 113739238 -114304896

Locus: 4q25-q26

ARHGAP10 Gene Summary

The Rho GTPase Activating Protein 10 (ARHGAP10) gene is located on chr4 :148653452-148993927 at 4q31.23.

Gene Name: Rho GTPase Activating Protein 10

Chromosome: CHR4: 148653452 -148993927

Locus: 4q31.23

Gene Diseases

The ANK2 ARHGAP10 Fusion has been associated with the following diseases:

Disease Name
Glioblastoma Multiforme

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.