ANAPC7-PAH Fusion FISH Probe
The ANAPC7-PAH Fusion FISH Probe is used to confirm a fusion of the ANAPC7 and PAH genes. The fusion of the ANAPC7 and PAH genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ANAPC7-PAH-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ANAPC7-PAH-20-RERE | 20 (40 μL) | 200 μL |
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| ANAPC7-PAH-20-REOR | 20 (40 μL) | 200 μL |
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| ANAPC7-PAH-20-REGO | 20 (40 μL) | 200 μL |
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| ANAPC7-PAH-20-REGR | 20 (40 μL) | 200 μL |
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| ANAPC7-PAH-20-REAQ | 20 (40 μL) | 200 μL |
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| ANAPC7-PAH-20-ORRE | 20 (40 μL) | 200 μL |
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| ANAPC7-PAH-20-OROR | 20 (40 μL) | 200 μL |
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| ANAPC7-PAH-20-ORGO | 20 (40 μL) | 200 μL |
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| ANAPC7-PAH-20-ORAQ | 20 (40 μL) | 200 μL |
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| ANAPC7-PAH-20-GORE | 20 (40 μL) | 200 μL |
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| ANAPC7-PAH-20-GOOR | 20 (40 μL) | 200 μL |
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| ANAPC7-PAH-20-GOGO | 20 (40 μL) | 200 μL |
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| ANAPC7-PAH-20-GOGR | 20 (40 μL) | 200 μL |
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| ANAPC7-PAH-20-GOAQ | 20 (40 μL) | 200 μL |
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| ANAPC7-PAH-20-GRRE | 20 (40 μL) | 200 μL |
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| ANAPC7-PAH-20-GROR | 20 (40 μL) | 200 μL |
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| ANAPC7-PAH-20-GRGO | 20 (40 μL) | 200 μL |
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| ANAPC7-PAH-20-GRGR | 20 (40 μL) | 200 μL |
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| ANAPC7-PAH-20-GRAQ | 20 (40 μL) | 200 μL |
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| ANAPC7-PAH-20-AQRE | 20 (40 μL) | 200 μL |
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| ANAPC7-PAH-20-AQOR | 20 (40 μL) | 200 μL |
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| ANAPC7-PAH-20-AQGO | 20 (40 μL) | 200 μL |
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| ANAPC7-PAH-20-AQGR | 20 (40 μL) | 200 μL |
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| ANAPC7-PAH-20-AQAQ | 20 (40 μL) | 200 μL |
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PAH Gene Summary
This gene encodes a member of the biopterin-dependent aromatic amino acid hydroxylase protein family. The encoded phenylalanine hydroxylase enzyme hydroxylates phenylalanine to tyrosine and is the rate-limiting step in phenylalanine catabolism. Deficiency of this enzyme activity results in the autosomal recessive disorder phenylketonuria. [provided by RefSeq, Aug 2017]
Gene Name: Phenylalanine Hydroxylase
Chromosome: CHR12: 103232103 -103311381
Locus: 12q23.2
ANAPC7 Gene Summary
This gene encodes a tetratricopeptide repeat containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for proper protein ubiquitination function of APC/C and for the interaction of APC/C with certain transcription coactivators. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]
Gene Name: Anaphase Promoting Complex Subunit 7
Chromosome: CHR12: 110810704 -110841535
Locus: 12q24.11
Gene Diseases
The ANAPC7 PAH Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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