ANAPC7-CORO1C Fusion FISH Probe
The ANAPC7-CORO1C Fusion FISH Probe is used to confirm a fusion of the ANAPC7 and CORO1C genes. The fusion of the ANAPC7 and CORO1C genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ANAPC7-CORO1C-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ANAPC7-CORO1C-20-RERE | 20 (40 μL) | 200 μL |
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| ANAPC7-CORO1C-20-REOR | 20 (40 μL) | 200 μL |
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| ANAPC7-CORO1C-20-REGO | 20 (40 μL) | 200 μL |
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| ANAPC7-CORO1C-20-REGR | 20 (40 μL) | 200 μL |
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| ANAPC7-CORO1C-20-REAQ | 20 (40 μL) | 200 μL |
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| ANAPC7-CORO1C-20-ORRE | 20 (40 μL) | 200 μL |
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| ANAPC7-CORO1C-20-OROR | 20 (40 μL) | 200 μL |
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| ANAPC7-CORO1C-20-ORGO | 20 (40 μL) | 200 μL |
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| ANAPC7-CORO1C-20-ORAQ | 20 (40 μL) | 200 μL |
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| ANAPC7-CORO1C-20-GORE | 20 (40 μL) | 200 μL |
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| ANAPC7-CORO1C-20-GOOR | 20 (40 μL) | 200 μL |
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| ANAPC7-CORO1C-20-GOGO | 20 (40 μL) | 200 μL |
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| ANAPC7-CORO1C-20-GOGR | 20 (40 μL) | 200 μL |
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| ANAPC7-CORO1C-20-GOAQ | 20 (40 μL) | 200 μL |
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| ANAPC7-CORO1C-20-GRRE | 20 (40 μL) | 200 μL |
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| ANAPC7-CORO1C-20-GROR | 20 (40 μL) | 200 μL |
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| ANAPC7-CORO1C-20-GRGO | 20 (40 μL) | 200 μL |
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| ANAPC7-CORO1C-20-GRGR | 20 (40 μL) | 200 μL |
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| ANAPC7-CORO1C-20-GRAQ | 20 (40 μL) | 200 μL |
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| ANAPC7-CORO1C-20-AQRE | 20 (40 μL) | 200 μL |
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| ANAPC7-CORO1C-20-AQOR | 20 (40 μL) | 200 μL |
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| ANAPC7-CORO1C-20-AQGO | 20 (40 μL) | 200 μL |
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| ANAPC7-CORO1C-20-AQGR | 20 (40 μL) | 200 μL |
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| ANAPC7-CORO1C-20-AQAQ | 20 (40 μL) | 200 μL |
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CORO1C Gene Summary
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2013]
Gene Name: Coronin 1C
Chromosome: CHR12: 109038886 -109125295
Locus: 12q24.11
ANAPC7 Gene Summary
This gene encodes a tetratricopeptide repeat containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for proper protein ubiquitination function of APC/C and for the interaction of APC/C with certain transcription coactivators. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]
Gene Name: Anaphase Promoting Complex Subunit 7
Chromosome: CHR12: 110810704 -110841535
Locus: 12q24.11
Gene Diseases
The ANAPC7 CORO1C Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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