ANAPC2-EYS Fusion FISH Probe
The ANAPC2-EYS Fusion FISH Probe is used to confirm a fusion of the ANAPC2 and EYS genes. The fusion of the ANAPC2 and EYS genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ANAPC2-EYS-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ANAPC2-EYS-20-RERE | 20 (40 μL) | 200 μL |
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| ANAPC2-EYS-20-REOR | 20 (40 μL) | 200 μL |
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| ANAPC2-EYS-20-REGO | 20 (40 μL) | 200 μL |
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| ANAPC2-EYS-20-REGR | 20 (40 μL) | 200 μL |
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| ANAPC2-EYS-20-REAQ | 20 (40 μL) | 200 μL |
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| ANAPC2-EYS-20-ORRE | 20 (40 μL) | 200 μL |
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| ANAPC2-EYS-20-OROR | 20 (40 μL) | 200 μL |
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| ANAPC2-EYS-20-ORGO | 20 (40 μL) | 200 μL |
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| ANAPC2-EYS-20-ORAQ | 20 (40 μL) | 200 μL |
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| ANAPC2-EYS-20-GORE | 20 (40 μL) | 200 μL |
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| ANAPC2-EYS-20-GOOR | 20 (40 μL) | 200 μL |
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| ANAPC2-EYS-20-GOGO | 20 (40 μL) | 200 μL |
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| ANAPC2-EYS-20-GOGR | 20 (40 μL) | 200 μL |
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| ANAPC2-EYS-20-GOAQ | 20 (40 μL) | 200 μL |
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| ANAPC2-EYS-20-GRRE | 20 (40 μL) | 200 μL |
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| ANAPC2-EYS-20-GROR | 20 (40 μL) | 200 μL |
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| ANAPC2-EYS-20-GRGO | 20 (40 μL) | 200 μL |
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| ANAPC2-EYS-20-GRGR | 20 (40 μL) | 200 μL |
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| ANAPC2-EYS-20-GRAQ | 20 (40 μL) | 200 μL |
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| ANAPC2-EYS-20-AQRE | 20 (40 μL) | 200 μL |
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| ANAPC2-EYS-20-AQOR | 20 (40 μL) | 200 μL |
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| ANAPC2-EYS-20-AQGO | 20 (40 μL) | 200 μL |
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| ANAPC2-EYS-20-AQGR | 20 (40 μL) | 200 μL |
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| ANAPC2-EYS-20-AQAQ | 20 (40 μL) | 200 μL |
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ANAPC2 Gene Summary
A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The product of this gene is a component of the complex and shares sequence similarity with a recently identified family of proteins called cullins, which may also be involved in ubiquitin-mediated degradation. [provided by RefSeq, Jul 2008]
Gene Name: Anaphase Promoting Complex Subunit 2
Chromosome: CHR9: 140069235 -140083057
Locus: 9q34.3
EYS Gene Summary
The product of this gene contains multiple epidermal growth factor (EGF)-like and LamG domains. The protein is expressed in the photoreceptor layer of the retina, and the gene is mutated in autosomal recessive retinitis pigmentosa. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
Gene Name: Eyes Shut Homolog (Drosophila)
Chromosome: CHR6: 64429875 -66417118
Locus: 6q12
Gene Diseases
The ANAPC2 EYS Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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