AMZ2-KDM1B Fusion FISH Probe
The AMZ2-KDM1B Fusion FISH Probe is used to confirm a fusion of the AMZ2 and KDM1B genes. The fusion of the AMZ2 and KDM1B genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| AMZ2-KDM1B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| AMZ2-KDM1B-20-RERE | 20 (40 μL) | 200 μL |
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| AMZ2-KDM1B-20-REOR | 20 (40 μL) | 200 μL |
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| AMZ2-KDM1B-20-REGO | 20 (40 μL) | 200 μL |
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| AMZ2-KDM1B-20-REGR | 20 (40 μL) | 200 μL |
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| AMZ2-KDM1B-20-REAQ | 20 (40 μL) | 200 μL |
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| AMZ2-KDM1B-20-ORRE | 20 (40 μL) | 200 μL |
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| AMZ2-KDM1B-20-OROR | 20 (40 μL) | 200 μL |
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| AMZ2-KDM1B-20-ORGO | 20 (40 μL) | 200 μL |
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| AMZ2-KDM1B-20-ORAQ | 20 (40 μL) | 200 μL |
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| AMZ2-KDM1B-20-GORE | 20 (40 μL) | 200 μL |
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| AMZ2-KDM1B-20-GOOR | 20 (40 μL) | 200 μL |
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| AMZ2-KDM1B-20-GOGO | 20 (40 μL) | 200 μL |
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| AMZ2-KDM1B-20-GOGR | 20 (40 μL) | 200 μL |
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| AMZ2-KDM1B-20-GOAQ | 20 (40 μL) | 200 μL |
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| AMZ2-KDM1B-20-GRRE | 20 (40 μL) | 200 μL |
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| AMZ2-KDM1B-20-GROR | 20 (40 μL) | 200 μL |
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| AMZ2-KDM1B-20-GRGO | 20 (40 μL) | 200 μL |
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| AMZ2-KDM1B-20-GRGR | 20 (40 μL) | 200 μL |
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| AMZ2-KDM1B-20-GRAQ | 20 (40 μL) | 200 μL |
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| AMZ2-KDM1B-20-AQRE | 20 (40 μL) | 200 μL |
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| AMZ2-KDM1B-20-AQOR | 20 (40 μL) | 200 μL |
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| AMZ2-KDM1B-20-AQGO | 20 (40 μL) | 200 μL |
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| AMZ2-KDM1B-20-AQGR | 20 (40 μL) | 200 μL |
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| AMZ2-KDM1B-20-AQAQ | 20 (40 μL) | 200 μL |
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AMZ2 Gene Summary
The protein encoded by this gene is a zinc metalloprotease that displays some activity against angiotensin-3. The encoded protein is inhibited by the aminopeptidase inhibitor amastatin, as well as by the general inhibitors o-phenanthroline and batimastat. Defects in this gene may be associated with lung tumorigenesis. [provided by RefSeq, Oct 2016]
Gene Name: Archaelysin Family Metallopeptidase 2
Chromosome: CHR17: 66244144 -66253305
Locus: 17q24.2
KDM1B Gene Summary
Flavin-dependent histone demethylases, such as KDM1B, regulate histone lysine methylation, an epigenetic mark that regulates gene expression and chromatin function (Karytinos et al., 2009 [PubMed 19407342]).[supplied by OMIM, Oct 2009]
Gene Name: Lysine Demethylase 1B
Chromosome: CHR6: 18155618 -18224084
Locus: 6p22.3
Gene Diseases
The AMZ2 KDM1B Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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