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AMOTL1-PIWIL4 Fusion FISH Probe

The AMOTL1-PIWIL4 Fusion FISH Probe is used to confirm a fusion of the AMOTL1 and PIWIL4 genes. The fusion of the AMOTL1 and PIWIL4 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
AMOTL1-PIWIL4-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
AMOTL1-PIWIL4-20-RERE 20 (40 μL) 200 μL
AMOTL1-PIWIL4-20-REOR 20 (40 μL) 200 μL
AMOTL1-PIWIL4-20-REGO 20 (40 μL) 200 μL
AMOTL1-PIWIL4-20-REGR 20 (40 μL) 200 μL
AMOTL1-PIWIL4-20-REAQ 20 (40 μL) 200 μL
AMOTL1-PIWIL4-20-ORRE 20 (40 μL) 200 μL
AMOTL1-PIWIL4-20-OROR 20 (40 μL) 200 μL
AMOTL1-PIWIL4-20-ORGO 20 (40 μL) 200 μL
AMOTL1-PIWIL4-20-ORAQ 20 (40 μL) 200 μL
AMOTL1-PIWIL4-20-GORE 20 (40 μL) 200 μL
AMOTL1-PIWIL4-20-GOOR 20 (40 μL) 200 μL
AMOTL1-PIWIL4-20-GOGO 20 (40 μL) 200 μL
AMOTL1-PIWIL4-20-GOGR 20 (40 μL) 200 μL
AMOTL1-PIWIL4-20-GOAQ 20 (40 μL) 200 μL
AMOTL1-PIWIL4-20-GRRE 20 (40 μL) 200 μL
AMOTL1-PIWIL4-20-GROR 20 (40 μL) 200 μL
AMOTL1-PIWIL4-20-GRGO 20 (40 μL) 200 μL
AMOTL1-PIWIL4-20-GRGR 20 (40 μL) 200 μL
AMOTL1-PIWIL4-20-GRAQ 20 (40 μL) 200 μL
AMOTL1-PIWIL4-20-AQRE 20 (40 μL) 200 μL
AMOTL1-PIWIL4-20-AQOR 20 (40 μL) 200 μL
AMOTL1-PIWIL4-20-AQGO 20 (40 μL) 200 μL
AMOTL1-PIWIL4-20-AQGR 20 (40 μL) 200 μL
AMOTL1-PIWIL4-20-AQAQ 20 (40 μL) 200 μL

PIWIL4 Gene Summary

PIWIL4 belongs to the Argonaute family of proteins, which function in development and maintenance of germline stem cells (Sasaki et al., 2003 [PubMed 12906857]).[supplied by OMIM, Mar 2008]

Gene Name: Piwi Like RNA-mediated Gene Silencing 4

Chromosome: CHR11: 94300473 -94354587

Locus: 11q21

AMOTL1 Gene Summary

The protein encoded by this gene is a peripheral membrane protein that is a component of tight junctions or TJs. TJs form an apical junctional structure and act to control paracellular permeability and maintain cell polarity. This protein is related to angiomotin, an angiostatin binding protein that regulates endothelial cell migration and capillary formation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]

Gene Name: Angiomotin Like 1

Chromosome: CHR11: 94501507 -94609918

Locus: 11q21

Gene Diseases

The AMOTL1 PIWIL4 Fusion has been associated with the following diseases:

Disease Name
Sarcoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.