AMOTL1-PIWIL4 Fusion FISH Probe
The AMOTL1-PIWIL4 Fusion FISH Probe is used to confirm a fusion of the AMOTL1 and PIWIL4 genes. The fusion of the AMOTL1 and PIWIL4 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| AMOTL1-PIWIL4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| AMOTL1-PIWIL4-20-RERE | 20 (40 μL) | 200 μL |
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| AMOTL1-PIWIL4-20-REOR | 20 (40 μL) | 200 μL |
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| AMOTL1-PIWIL4-20-REGO | 20 (40 μL) | 200 μL |
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| AMOTL1-PIWIL4-20-REGR | 20 (40 μL) | 200 μL |
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| AMOTL1-PIWIL4-20-REAQ | 20 (40 μL) | 200 μL |
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| AMOTL1-PIWIL4-20-ORRE | 20 (40 μL) | 200 μL |
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| AMOTL1-PIWIL4-20-OROR | 20 (40 μL) | 200 μL |
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| AMOTL1-PIWIL4-20-ORGO | 20 (40 μL) | 200 μL |
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| AMOTL1-PIWIL4-20-ORAQ | 20 (40 μL) | 200 μL |
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| AMOTL1-PIWIL4-20-GORE | 20 (40 μL) | 200 μL |
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| AMOTL1-PIWIL4-20-GOOR | 20 (40 μL) | 200 μL |
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| AMOTL1-PIWIL4-20-GOGO | 20 (40 μL) | 200 μL |
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| AMOTL1-PIWIL4-20-GOGR | 20 (40 μL) | 200 μL |
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| AMOTL1-PIWIL4-20-GOAQ | 20 (40 μL) | 200 μL |
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| AMOTL1-PIWIL4-20-GRRE | 20 (40 μL) | 200 μL |
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| AMOTL1-PIWIL4-20-GROR | 20 (40 μL) | 200 μL |
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| AMOTL1-PIWIL4-20-GRGO | 20 (40 μL) | 200 μL |
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| AMOTL1-PIWIL4-20-GRGR | 20 (40 μL) | 200 μL |
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| AMOTL1-PIWIL4-20-GRAQ | 20 (40 μL) | 200 μL |
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| AMOTL1-PIWIL4-20-AQRE | 20 (40 μL) | 200 μL |
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| AMOTL1-PIWIL4-20-AQOR | 20 (40 μL) | 200 μL |
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| AMOTL1-PIWIL4-20-AQGO | 20 (40 μL) | 200 μL |
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| AMOTL1-PIWIL4-20-AQGR | 20 (40 μL) | 200 μL |
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| AMOTL1-PIWIL4-20-AQAQ | 20 (40 μL) | 200 μL |
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PIWIL4 Gene Summary
PIWIL4 belongs to the Argonaute family of proteins, which function in development and maintenance of germline stem cells (Sasaki et al., 2003 [PubMed 12906857]).[supplied by OMIM, Mar 2008]
Gene Name: Piwi Like RNA-mediated Gene Silencing 4
Chromosome: CHR11: 94300473 -94354587
Locus: 11q21
AMOTL1 Gene Summary
The protein encoded by this gene is a peripheral membrane protein that is a component of tight junctions or TJs. TJs form an apical junctional structure and act to control paracellular permeability and maintain cell polarity. This protein is related to angiomotin, an angiostatin binding protein that regulates endothelial cell migration and capillary formation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
Gene Name: Angiomotin Like 1
Chromosome: CHR11: 94501507 -94609918
Locus: 11q21
Gene Diseases
The AMOTL1 PIWIL4 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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