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AMBRA1-CAT Fusion FISH Probe

The AMBRA1-CAT Fusion FISH Probe is used to confirm a fusion of the AMBRA1 and CAT genes. The fusion of the AMBRA1 and CAT genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
AMBRA1-CAT-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
AMBRA1-CAT-20-RERE 20 (40 μL) 200 μL
AMBRA1-CAT-20-REOR 20 (40 μL) 200 μL
AMBRA1-CAT-20-REGO 20 (40 μL) 200 μL
AMBRA1-CAT-20-REGR 20 (40 μL) 200 μL
AMBRA1-CAT-20-REAQ 20 (40 μL) 200 μL
AMBRA1-CAT-20-ORRE 20 (40 μL) 200 μL
AMBRA1-CAT-20-OROR 20 (40 μL) 200 μL
AMBRA1-CAT-20-ORGO 20 (40 μL) 200 μL
AMBRA1-CAT-20-ORAQ 20 (40 μL) 200 μL
AMBRA1-CAT-20-GORE 20 (40 μL) 200 μL
AMBRA1-CAT-20-GOOR 20 (40 μL) 200 μL
AMBRA1-CAT-20-GOGO 20 (40 μL) 200 μL
AMBRA1-CAT-20-GOGR 20 (40 μL) 200 μL
AMBRA1-CAT-20-GOAQ 20 (40 μL) 200 μL
AMBRA1-CAT-20-GRRE 20 (40 μL) 200 μL
AMBRA1-CAT-20-GROR 20 (40 μL) 200 μL
AMBRA1-CAT-20-GRGO 20 (40 μL) 200 μL
AMBRA1-CAT-20-GRGR 20 (40 μL) 200 μL
AMBRA1-CAT-20-GRAQ 20 (40 μL) 200 μL
AMBRA1-CAT-20-AQRE 20 (40 μL) 200 μL
AMBRA1-CAT-20-AQOR 20 (40 μL) 200 μL
AMBRA1-CAT-20-AQGO 20 (40 μL) 200 μL
AMBRA1-CAT-20-AQGR 20 (40 μL) 200 μL
AMBRA1-CAT-20-AQAQ 20 (40 μL) 200 μL

CAT Gene Summary

This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene. [provided by RefSeq, Oct 2009]

Gene Name: Catalase

Chromosome: CHR11: 34460471 -34493607

Locus: 11p13

AMBRA1 Gene Summary

The Autophagy And Beclin 1 Regulator 1 (AMBRA1) gene is located on chr11 :46417963-46612914 at 11p11.2.

Gene Name: Autophagy And Beclin 1 Regulator 1

Chromosome: CHR11: 46417963 -46612914

Locus: 11p11.2

Gene Diseases

The AMBRA1 CAT Fusion has been associated with the following diseases:

Disease Name
Stomach Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.