AMBP-SEC63 Fusion FISH Probe
The AMBP-SEC63 Fusion FISH Probe is used to confirm a fusion of the AMBP and SEC63 genes. The fusion of the AMBP and SEC63 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| AMBP-SEC63-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| AMBP-SEC63-20-RERE | 20 (40 μL) | 200 μL |
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| AMBP-SEC63-20-REOR | 20 (40 μL) | 200 μL |
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| AMBP-SEC63-20-REGO | 20 (40 μL) | 200 μL |
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| AMBP-SEC63-20-REGR | 20 (40 μL) | 200 μL |
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| AMBP-SEC63-20-REAQ | 20 (40 μL) | 200 μL |
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| AMBP-SEC63-20-ORRE | 20 (40 μL) | 200 μL |
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| AMBP-SEC63-20-OROR | 20 (40 μL) | 200 μL |
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| AMBP-SEC63-20-ORGO | 20 (40 μL) | 200 μL |
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| AMBP-SEC63-20-ORAQ | 20 (40 μL) | 200 μL |
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| AMBP-SEC63-20-GORE | 20 (40 μL) | 200 μL |
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| AMBP-SEC63-20-GOOR | 20 (40 μL) | 200 μL |
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| AMBP-SEC63-20-GOGO | 20 (40 μL) | 200 μL |
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| AMBP-SEC63-20-GOGR | 20 (40 μL) | 200 μL |
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| AMBP-SEC63-20-GOAQ | 20 (40 μL) | 200 μL |
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| AMBP-SEC63-20-GRRE | 20 (40 μL) | 200 μL |
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| AMBP-SEC63-20-GROR | 20 (40 μL) | 200 μL |
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| AMBP-SEC63-20-GRGO | 20 (40 μL) | 200 μL |
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| AMBP-SEC63-20-GRGR | 20 (40 μL) | 200 μL |
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| AMBP-SEC63-20-GRAQ | 20 (40 μL) | 200 μL |
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| AMBP-SEC63-20-AQRE | 20 (40 μL) | 200 μL |
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| AMBP-SEC63-20-AQOR | 20 (40 μL) | 200 μL |
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| AMBP-SEC63-20-AQGO | 20 (40 μL) | 200 μL |
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| AMBP-SEC63-20-AQGR | 20 (40 μL) | 200 μL |
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| AMBP-SEC63-20-AQAQ | 20 (40 μL) | 200 μL |
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AMBP Gene Summary
This gene encodes a complex glycoprotein secreted in plasma. The precursor is proteolytically processed into distinct functioning proteins: alpha-1-microglobulin, which belongs to the superfamily of lipocalin transport proteins and may play a role in the regulation of inflammatory processes, and bikunin, which is a urinary trypsin inhibitor belonging to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes. This gene is located on chromosome 9 in a cluster of lipocalin genes. [provided by RefSeq, Jul 2008]
Gene Name: Alpha-1-microglobulin/bikunin Precursor
Chromosome: CHR9: 116822407 -116840752
Locus: 9q32
SEC63 Gene Summary
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. [provided by RefSeq, Jul 2008]
Gene Name: SEC63 Homolog, Protein Translocation Regulator
Chromosome: CHR6: 108188959 -108279482
Locus: 6q21
Gene Diseases
The AMBP SEC63 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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