ALX4-STK33 Fusion FISH Probe
The ALX4-STK33 Fusion FISH Probe is used to confirm a fusion of the ALX4 and STK33 genes. The fusion of the ALX4 and STK33 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ALX4-STK33-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| ALX4-STK33-20-RERE | 20 (40 μL) | 200 μL |
|
|
| ALX4-STK33-20-REOR | 20 (40 μL) | 200 μL |
|
|
| ALX4-STK33-20-REGO | 20 (40 μL) | 200 μL |
|
|
| ALX4-STK33-20-REGR | 20 (40 μL) | 200 μL |
|
|
| ALX4-STK33-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| ALX4-STK33-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| ALX4-STK33-20-OROR | 20 (40 μL) | 200 μL |
|
|
| ALX4-STK33-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| ALX4-STK33-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| ALX4-STK33-20-GORE | 20 (40 μL) | 200 μL |
|
|
| ALX4-STK33-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| ALX4-STK33-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| ALX4-STK33-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| ALX4-STK33-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| ALX4-STK33-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| ALX4-STK33-20-GROR | 20 (40 μL) | 200 μL |
|
|
| ALX4-STK33-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| ALX4-STK33-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| ALX4-STK33-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| ALX4-STK33-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| ALX4-STK33-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| ALX4-STK33-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| ALX4-STK33-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| ALX4-STK33-20-AQAQ | 20 (40 μL) | 200 μL |
|
ALX4 Gene Summary
This gene encodes a paired-like homeodomain transcription factor expressed in the mesenchyme of developing bones, limbs, hair, teeth, and mammary tissue. Mutations in this gene cause parietal foramina 2 (PFM2); an autosomal dominant disease characterized by deficient ossification of the parietal bones. Mutations in this gene also cause a form of frontonasal dysplasia with alopecia and hypogonadism; suggesting a role for this gene in craniofacial development, mesenchymal-epithelial communication, and hair follicle development. Deletion of a segment of chromosome 11 containing this gene, del(11)(p11p12), causes Potocki-Shaffer syndrome (PSS); a syndrome characterized by craniofacial anomalies, cognitive disability, multiple exostoses, and genital abnormalities in males. In mouse, this gene has been shown to use dual translation initiation sites located 16 codons apart. [provided by RefSeq, Oct 2009]
Gene Name: ALX Homeobox 4
Chromosome: CHR11: 44282277 -44331716
Locus: 11p11.2
STK33 Gene Summary
The Serine/threonine Kinase 33 (STK33) gene is located on chr11 :8413417-8615503 at 11p15.4.
Gene Name: Serine/threonine Kinase 33
Chromosome: CHR11: 8413417 -8615503
Locus: 11p15.4
Gene Diseases
The ALX4 STK33 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|