ALPL-FILIP1L Fusion FISH Probe
The ALPL-FILIP1L Fusion FISH Probe is used to confirm a fusion of the ALPL and FILIP1L genes. The fusion of the ALPL and FILIP1L genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ALPL-FILIP1L-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ALPL-FILIP1L-20-RERE | 20 (40 μL) | 200 μL |
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| ALPL-FILIP1L-20-REOR | 20 (40 μL) | 200 μL |
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| ALPL-FILIP1L-20-REGO | 20 (40 μL) | 200 μL |
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| ALPL-FILIP1L-20-REGR | 20 (40 μL) | 200 μL |
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| ALPL-FILIP1L-20-REAQ | 20 (40 μL) | 200 μL |
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| ALPL-FILIP1L-20-ORRE | 20 (40 μL) | 200 μL |
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| ALPL-FILIP1L-20-OROR | 20 (40 μL) | 200 μL |
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| ALPL-FILIP1L-20-ORGO | 20 (40 μL) | 200 μL |
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| ALPL-FILIP1L-20-ORAQ | 20 (40 μL) | 200 μL |
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| ALPL-FILIP1L-20-GORE | 20 (40 μL) | 200 μL |
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| ALPL-FILIP1L-20-GOOR | 20 (40 μL) | 200 μL |
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| ALPL-FILIP1L-20-GOGO | 20 (40 μL) | 200 μL |
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| ALPL-FILIP1L-20-GOGR | 20 (40 μL) | 200 μL |
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| ALPL-FILIP1L-20-GOAQ | 20 (40 μL) | 200 μL |
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| ALPL-FILIP1L-20-GRRE | 20 (40 μL) | 200 μL |
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| ALPL-FILIP1L-20-GROR | 20 (40 μL) | 200 μL |
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| ALPL-FILIP1L-20-GRGO | 20 (40 μL) | 200 μL |
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| ALPL-FILIP1L-20-GRGR | 20 (40 μL) | 200 μL |
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| ALPL-FILIP1L-20-GRAQ | 20 (40 μL) | 200 μL |
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| ALPL-FILIP1L-20-AQRE | 20 (40 μL) | 200 μL |
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| ALPL-FILIP1L-20-AQOR | 20 (40 μL) | 200 μL |
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| ALPL-FILIP1L-20-AQGO | 20 (40 μL) | 200 μL |
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| ALPL-FILIP1L-20-AQGR | 20 (40 μL) | 200 μL |
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| ALPL-FILIP1L-20-AQAQ | 20 (40 μL) | 200 μL |
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ALPL Gene Summary
This gene encodes a member of the alkaline phosphatase family of proteins. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme may play a role in bone mineralization. Mutations in this gene have been linked to hypophosphatasia, a disorder that is characterized by hypercalcemia and skeletal defects. [provided by RefSeq, Oct 2015]
Gene Name: Alkaline Phosphatase, Liver/bone/kidney
Chromosome: CHR1: 21835857 -21904905
Locus: 1p36.12
FILIP1L Gene Summary
The Filamin A Interacting Protein 1 Like (FILIP1L) gene is located on chr3 :99551987-99833349 at 3q12.1.
Gene Name: Filamin A Interacting Protein 1 Like
Chromosome: CHR3: 99551987 -99833349
Locus: 3q12.1
Gene Diseases
The ALPL FILIP1L Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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