ALG8-FGF19 Fusion FISH Probe
The ALG8-FGF19 Fusion FISH Probe is used to confirm a fusion of the ALG8 and FGF19 genes. The fusion of the ALG8 and FGF19 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ALG8-FGF19-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ALG8-FGF19-20-RERE | 20 (40 μL) | 200 μL |
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| ALG8-FGF19-20-REOR | 20 (40 μL) | 200 μL |
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| ALG8-FGF19-20-REGO | 20 (40 μL) | 200 μL |
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| ALG8-FGF19-20-REGR | 20 (40 μL) | 200 μL |
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| ALG8-FGF19-20-REAQ | 20 (40 μL) | 200 μL |
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| ALG8-FGF19-20-ORRE | 20 (40 μL) | 200 μL |
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| ALG8-FGF19-20-OROR | 20 (40 μL) | 200 μL |
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| ALG8-FGF19-20-ORGO | 20 (40 μL) | 200 μL |
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| ALG8-FGF19-20-ORAQ | 20 (40 μL) | 200 μL |
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| ALG8-FGF19-20-GORE | 20 (40 μL) | 200 μL |
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| ALG8-FGF19-20-GOOR | 20 (40 μL) | 200 μL |
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| ALG8-FGF19-20-GOGO | 20 (40 μL) | 200 μL |
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| ALG8-FGF19-20-GOGR | 20 (40 μL) | 200 μL |
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| ALG8-FGF19-20-GOAQ | 20 (40 μL) | 200 μL |
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| ALG8-FGF19-20-GRRE | 20 (40 μL) | 200 μL |
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| ALG8-FGF19-20-GROR | 20 (40 μL) | 200 μL |
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| ALG8-FGF19-20-GRGO | 20 (40 μL) | 200 μL |
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| ALG8-FGF19-20-GRGR | 20 (40 μL) | 200 μL |
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| ALG8-FGF19-20-GRAQ | 20 (40 μL) | 200 μL |
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| ALG8-FGF19-20-AQRE | 20 (40 μL) | 200 μL |
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| ALG8-FGF19-20-AQOR | 20 (40 μL) | 200 μL |
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| ALG8-FGF19-20-AQGO | 20 (40 μL) | 200 μL |
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| ALG8-FGF19-20-AQGR | 20 (40 μL) | 200 μL |
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| ALG8-FGF19-20-AQAQ | 20 (40 μL) | 200 μL |
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FGF19 Gene Summary
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth and invasion. This growth factor is a high affinity, heparin dependent ligand for FGFR4. Expression of this gene was detected only in fetal but not adult brain tissue. Synergistic interaction of the chick homolog and Wnt-8c has been shown to be required for initiation of inner ear development. [provided by RefSeq, Jul 2008]
Gene Name: Fibroblast Growth Factor 19
Chromosome: CHR11: 69513005 -69519106
Locus: 11q13.3
ALG8 Gene Summary
This gene encodes a member of the ALG6/ALG8 glucosyltransferase family. The encoded protein catalyzes the addition of the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation of proteins. Mutations in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ih). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Name: ALG8, Alpha-1,3-glucosyltransferase
Chromosome: CHR11: 77811987 -77850699
Locus: 11q14.1
Gene Diseases
The ALG8 FGF19 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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