ALG14-JAK1 Fusion FISH Probe
The ALG14-JAK1 Fusion FISH Probe is used to confirm a fusion of the ALG14 and JAK1 genes. The fusion of the ALG14 and JAK1 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ALG14-JAK1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ALG14-JAK1-20-RERE | 20 (40 μL) | 200 μL |
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| ALG14-JAK1-20-REOR | 20 (40 μL) | 200 μL |
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| ALG14-JAK1-20-REGO | 20 (40 μL) | 200 μL |
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| ALG14-JAK1-20-REGR | 20 (40 μL) | 200 μL |
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| ALG14-JAK1-20-REAQ | 20 (40 μL) | 200 μL |
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| ALG14-JAK1-20-ORRE | 20 (40 μL) | 200 μL |
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| ALG14-JAK1-20-OROR | 20 (40 μL) | 200 μL |
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| ALG14-JAK1-20-ORGO | 20 (40 μL) | 200 μL |
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| ALG14-JAK1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ALG14-JAK1-20-GORE | 20 (40 μL) | 200 μL |
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| ALG14-JAK1-20-GOOR | 20 (40 μL) | 200 μL |
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| ALG14-JAK1-20-GOGO | 20 (40 μL) | 200 μL |
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| ALG14-JAK1-20-GOGR | 20 (40 μL) | 200 μL |
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| ALG14-JAK1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ALG14-JAK1-20-GRRE | 20 (40 μL) | 200 μL |
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| ALG14-JAK1-20-GROR | 20 (40 μL) | 200 μL |
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| ALG14-JAK1-20-GRGO | 20 (40 μL) | 200 μL |
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| ALG14-JAK1-20-GRGR | 20 (40 μL) | 200 μL |
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| ALG14-JAK1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ALG14-JAK1-20-AQRE | 20 (40 μL) | 200 μL |
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| ALG14-JAK1-20-AQOR | 20 (40 μL) | 200 μL |
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| ALG14-JAK1-20-AQGO | 20 (40 μL) | 200 μL |
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| ALG14-JAK1-20-AQGR | 20 (40 μL) | 200 μL |
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| ALG14-JAK1-20-AQAQ | 20 (40 μL) | 200 μL |
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JAK1 Gene Summary
This gene encodes a membrane protein that is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The encoded kinase phosphorylates STAT proteins (signal transducers and activators of transcription) and plays a key role in interferon-alpha/beta and interferon-gamma signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Gene Name: Janus Kinase 1
Chromosome: CHR1: 65298905 -65432187
Locus: 1p31.3
ALG14 Gene Summary
This gene is a member of the glycosyltransferase 1 family. The encoded protein and ALG13 are thought to be subunits of UDP-GlcNAc transferase, which catalyzes the first two committed steps in endoplasmic reticulum N-linked glycosylation. Mutations in this gene have been linked to congenital myasthenic syndrome (CMSWTA). Alternatively spliced transcript variants have been identified. [provided by RefSeq, Mar 2015]
Gene Name: ALG14, UDP-N-acetylglucosaminyltransferase Subunit
Chromosome: CHR1: 95448278 -95538507
Locus: 1p21.3
Gene Diseases
The ALG14 JAK1 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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