ALG12-CDT1 Fusion FISH Probe
The ALG12-CDT1 Fusion FISH Probe is used to confirm a fusion of the ALG12 and CDT1 genes. The fusion of the ALG12 and CDT1 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ALG12-CDT1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ALG12-CDT1-20-RERE | 20 (40 μL) | 200 μL |
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| ALG12-CDT1-20-REOR | 20 (40 μL) | 200 μL |
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| ALG12-CDT1-20-REGO | 20 (40 μL) | 200 μL |
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| ALG12-CDT1-20-REGR | 20 (40 μL) | 200 μL |
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| ALG12-CDT1-20-REAQ | 20 (40 μL) | 200 μL |
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| ALG12-CDT1-20-ORRE | 20 (40 μL) | 200 μL |
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| ALG12-CDT1-20-OROR | 20 (40 μL) | 200 μL |
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| ALG12-CDT1-20-ORGO | 20 (40 μL) | 200 μL |
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| ALG12-CDT1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ALG12-CDT1-20-GORE | 20 (40 μL) | 200 μL |
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| ALG12-CDT1-20-GOOR | 20 (40 μL) | 200 μL |
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| ALG12-CDT1-20-GOGO | 20 (40 μL) | 200 μL |
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| ALG12-CDT1-20-GOGR | 20 (40 μL) | 200 μL |
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| ALG12-CDT1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ALG12-CDT1-20-GRRE | 20 (40 μL) | 200 μL |
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| ALG12-CDT1-20-GROR | 20 (40 μL) | 200 μL |
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| ALG12-CDT1-20-GRGO | 20 (40 μL) | 200 μL |
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| ALG12-CDT1-20-GRGR | 20 (40 μL) | 200 μL |
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| ALG12-CDT1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ALG12-CDT1-20-AQRE | 20 (40 μL) | 200 μL |
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| ALG12-CDT1-20-AQOR | 20 (40 μL) | 200 μL |
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| ALG12-CDT1-20-AQGO | 20 (40 μL) | 200 μL |
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| ALG12-CDT1-20-AQGR | 20 (40 μL) | 200 μL |
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| ALG12-CDT1-20-AQAQ | 20 (40 μL) | 200 μL |
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ALG12 Gene Summary
This gene encodes a member of the glycosyltransferase 22 family. The encoded protein catalyzes the addition of the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP-Man(7)GlcNAc(2)) required for protein glycosylation. Mutations in this gene have been associated with congenital disorder of glycosylation type Ig (CDG-Ig)characterized by abnormal N-glycosylation. [provided by RefSeq, Jul 2008]
Gene Name: ALG12, Alpha-1,6-mannosyltransferase
Chromosome: CHR22: 50296853 -50312106
Locus: 22q13.33
CDT1 Gene Summary
The protein encoded by this gene is involved in the formation of the pre-replication complex that is necessary for DNA replication. The encoded protein can bind geminin, which prevents replication and may function to prevent this protein from initiating replication at inappropriate origins. Phosphorylation of this protein by cyclin A-dependent kinases results in degradation of the protein. [provided by RefSeq, Mar 2011]
Gene Name: Chromatin Licensing And DNA Replication Factor 1
Chromosome: CHR16: 88870185 -88875666
Locus: 16q24.3
Gene Diseases
The ALG12 CDT1 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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