ALDOA-SIAE Fusion FISH Probe
The ALDOA-SIAE Fusion FISH Probe is used to confirm a fusion of the ALDOA and SIAE genes. The fusion of the ALDOA and SIAE genes has been associated with Kidney Renal Papillary Cell Carcinoma, and Kidney Renal Papillary Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ALDOA-SIAE-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ALDOA-SIAE-20-RERE | 20 (40 μL) | 200 μL |
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| ALDOA-SIAE-20-REOR | 20 (40 μL) | 200 μL |
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| ALDOA-SIAE-20-REGO | 20 (40 μL) | 200 μL |
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| ALDOA-SIAE-20-REGR | 20 (40 μL) | 200 μL |
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| ALDOA-SIAE-20-REAQ | 20 (40 μL) | 200 μL |
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| ALDOA-SIAE-20-ORRE | 20 (40 μL) | 200 μL |
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| ALDOA-SIAE-20-OROR | 20 (40 μL) | 200 μL |
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| ALDOA-SIAE-20-ORGO | 20 (40 μL) | 200 μL |
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| ALDOA-SIAE-20-ORAQ | 20 (40 μL) | 200 μL |
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| ALDOA-SIAE-20-GORE | 20 (40 μL) | 200 μL |
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| ALDOA-SIAE-20-GOOR | 20 (40 μL) | 200 μL |
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| ALDOA-SIAE-20-GOGO | 20 (40 μL) | 200 μL |
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| ALDOA-SIAE-20-GOGR | 20 (40 μL) | 200 μL |
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| ALDOA-SIAE-20-GOAQ | 20 (40 μL) | 200 μL |
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| ALDOA-SIAE-20-GRRE | 20 (40 μL) | 200 μL |
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| ALDOA-SIAE-20-GROR | 20 (40 μL) | 200 μL |
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| ALDOA-SIAE-20-GRGO | 20 (40 μL) | 200 μL |
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| ALDOA-SIAE-20-GRGR | 20 (40 μL) | 200 μL |
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| ALDOA-SIAE-20-GRAQ | 20 (40 μL) | 200 μL |
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| ALDOA-SIAE-20-AQRE | 20 (40 μL) | 200 μL |
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| ALDOA-SIAE-20-AQOR | 20 (40 μL) | 200 μL |
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| ALDOA-SIAE-20-AQGO | 20 (40 μL) | 200 μL |
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| ALDOA-SIAE-20-AQGR | 20 (40 μL) | 200 μL |
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| ALDOA-SIAE-20-AQAQ | 20 (40 μL) | 200 μL |
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ALDOA Gene Summary
This gene encodes a member of the class I fructose-bisphosphate aldolase protein family. The encoded protein is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Mutations in this gene have been associated with Glycogen Storage Disease XII, an autosomal recessive disorder associated with hemolytic anemia. Disruption of this gene also plays a role in the progression of multiple types of cancers. Related pseudogenes have been identified on chromosomes 3 and 10. [provided by RefSeq, Sep 2017]
Gene Name: Aldolase, Fructose-bisphosphate A
Chromosome: CHR16: 30064410 -30081741
Locus: 16p11.2
SIAE Gene Summary
This gene encodes an enzyme which removes 9-O-acetylation modifications from sialic acids. Mutations in this gene are associated with susceptibility to autoimmune disease 6. Multiple transcript variants encoding different isoforms, found either in the cytosol or in the lysosome, have been found for this gene.[provided by RefSeq, Feb 2011]
Gene Name: Sialic Acid Acetylesterase
Chromosome: CHR11: 124505684 -124546199
Locus: 11q24.2
Gene Diseases
The ALDOA SIAE Fusion has been associated with the following diseases:
| Disease Name |
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| Kidney Renal Papillary Cell Carcinoma |
| Kidney Renal Papillary Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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