ALDOA-SCN2A Fusion FISH Probe
The ALDOA-SCN2A Fusion FISH Probe is used to confirm a fusion of the ALDOA and SCN2A genes. The fusion of the ALDOA and SCN2A genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ALDOA-SCN2A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ALDOA-SCN2A-20-RERE | 20 (40 μL) | 200 μL |
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| ALDOA-SCN2A-20-REOR | 20 (40 μL) | 200 μL |
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| ALDOA-SCN2A-20-REGO | 20 (40 μL) | 200 μL |
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| ALDOA-SCN2A-20-REGR | 20 (40 μL) | 200 μL |
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| ALDOA-SCN2A-20-REAQ | 20 (40 μL) | 200 μL |
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| ALDOA-SCN2A-20-ORRE | 20 (40 μL) | 200 μL |
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| ALDOA-SCN2A-20-OROR | 20 (40 μL) | 200 μL |
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| ALDOA-SCN2A-20-ORGO | 20 (40 μL) | 200 μL |
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| ALDOA-SCN2A-20-ORAQ | 20 (40 μL) | 200 μL |
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| ALDOA-SCN2A-20-GORE | 20 (40 μL) | 200 μL |
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| ALDOA-SCN2A-20-GOOR | 20 (40 μL) | 200 μL |
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| ALDOA-SCN2A-20-GOGO | 20 (40 μL) | 200 μL |
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| ALDOA-SCN2A-20-GOGR | 20 (40 μL) | 200 μL |
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| ALDOA-SCN2A-20-GOAQ | 20 (40 μL) | 200 μL |
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| ALDOA-SCN2A-20-GRRE | 20 (40 μL) | 200 μL |
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| ALDOA-SCN2A-20-GROR | 20 (40 μL) | 200 μL |
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| ALDOA-SCN2A-20-GRGO | 20 (40 μL) | 200 μL |
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| ALDOA-SCN2A-20-GRGR | 20 (40 μL) | 200 μL |
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| ALDOA-SCN2A-20-GRAQ | 20 (40 μL) | 200 μL |
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| ALDOA-SCN2A-20-AQRE | 20 (40 μL) | 200 μL |
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| ALDOA-SCN2A-20-AQOR | 20 (40 μL) | 200 μL |
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| ALDOA-SCN2A-20-AQGO | 20 (40 μL) | 200 μL |
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| ALDOA-SCN2A-20-AQGR | 20 (40 μL) | 200 μL |
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| ALDOA-SCN2A-20-AQAQ | 20 (40 μL) | 200 μL |
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ALDOA Gene Summary
This gene encodes a member of the class I fructose-bisphosphate aldolase protein family. The encoded protein is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Mutations in this gene have been associated with Glycogen Storage Disease XII, an autosomal recessive disorder associated with hemolytic anemia. Disruption of this gene also plays a role in the progression of multiple types of cancers. Related pseudogenes have been identified on chromosomes 3 and 10. [provided by RefSeq, Sep 2017]
Gene Name: Aldolase, Fructose-bisphosphate A
Chromosome: CHR16: 30064410 -30081741
Locus: 16p11.2
SCN2A Gene Summary
Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with four repeat domains, each of which is composed of six membrane-spanning segments, and one or more regulatory beta subunits. Voltage-gated sodium channels function in the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family. Allelic variants of this gene are associated with seizure disorders and autism spectrum disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016]
Gene Name: Sodium Voltage-gated Channel Alpha Subunit 2
Chromosome: CHR2: 166095911 -166248820
Locus: 2q24.3
Gene Diseases
The ALDOA SCN2A Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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