ALDOA-FADS2 Fusion FISH Probe
The ALDOA-FADS2 Fusion FISH Probe is used to confirm a fusion of the ALDOA and FADS2 genes. The fusion of the ALDOA and FADS2 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ALDOA-FADS2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ALDOA-FADS2-20-RERE | 20 (40 μL) | 200 μL |
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| ALDOA-FADS2-20-REOR | 20 (40 μL) | 200 μL |
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| ALDOA-FADS2-20-REGO | 20 (40 μL) | 200 μL |
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| ALDOA-FADS2-20-REGR | 20 (40 μL) | 200 μL |
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| ALDOA-FADS2-20-REAQ | 20 (40 μL) | 200 μL |
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| ALDOA-FADS2-20-ORRE | 20 (40 μL) | 200 μL |
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| ALDOA-FADS2-20-OROR | 20 (40 μL) | 200 μL |
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| ALDOA-FADS2-20-ORGO | 20 (40 μL) | 200 μL |
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| ALDOA-FADS2-20-ORAQ | 20 (40 μL) | 200 μL |
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| ALDOA-FADS2-20-GORE | 20 (40 μL) | 200 μL |
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| ALDOA-FADS2-20-GOOR | 20 (40 μL) | 200 μL |
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| ALDOA-FADS2-20-GOGO | 20 (40 μL) | 200 μL |
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| ALDOA-FADS2-20-GOGR | 20 (40 μL) | 200 μL |
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| ALDOA-FADS2-20-GOAQ | 20 (40 μL) | 200 μL |
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| ALDOA-FADS2-20-GRRE | 20 (40 μL) | 200 μL |
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| ALDOA-FADS2-20-GROR | 20 (40 μL) | 200 μL |
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| ALDOA-FADS2-20-GRGO | 20 (40 μL) | 200 μL |
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| ALDOA-FADS2-20-GRGR | 20 (40 μL) | 200 μL |
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| ALDOA-FADS2-20-GRAQ | 20 (40 μL) | 200 μL |
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| ALDOA-FADS2-20-AQRE | 20 (40 μL) | 200 μL |
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| ALDOA-FADS2-20-AQOR | 20 (40 μL) | 200 μL |
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| ALDOA-FADS2-20-AQGO | 20 (40 μL) | 200 μL |
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| ALDOA-FADS2-20-AQGR | 20 (40 μL) | 200 μL |
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| ALDOA-FADS2-20-AQAQ | 20 (40 μL) | 200 μL |
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ALDOA Gene Summary
This gene encodes a member of the class I fructose-bisphosphate aldolase protein family. The encoded protein is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Mutations in this gene have been associated with Glycogen Storage Disease XII, an autosomal recessive disorder associated with hemolytic anemia. Disruption of this gene also plays a role in the progression of multiple types of cancers. Related pseudogenes have been identified on chromosomes 3 and 10. [provided by RefSeq, Sep 2017]
Gene Name: Aldolase, Fructose-bisphosphate A
Chromosome: CHR16: 30064410 -30081741
Locus: 16p11.2
FADS2 Gene Summary
The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]
Gene Name: Fatty Acid Desaturase 2
Chromosome: CHR11: 61595712 -61634825
Locus: 11q12.2
Gene Diseases
The ALDOA FADS2 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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