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ALDOA-DDX27 Fusion FISH Probe

The ALDOA-DDX27 Fusion FISH Probe is used to confirm a fusion of the ALDOA and DDX27 genes. The fusion of the ALDOA and DDX27 genes has been associated with Rectum Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ALDOA-DDX27-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
ALDOA-DDX27-20-RERE 20 (40 μL) 200 μL
ALDOA-DDX27-20-REOR 20 (40 μL) 200 μL
ALDOA-DDX27-20-REGO 20 (40 μL) 200 μL
ALDOA-DDX27-20-REGR 20 (40 μL) 200 μL
ALDOA-DDX27-20-REAQ 20 (40 μL) 200 μL
ALDOA-DDX27-20-ORRE 20 (40 μL) 200 μL
ALDOA-DDX27-20-OROR 20 (40 μL) 200 μL
ALDOA-DDX27-20-ORGO 20 (40 μL) 200 μL
ALDOA-DDX27-20-ORAQ 20 (40 μL) 200 μL
ALDOA-DDX27-20-GORE 20 (40 μL) 200 μL
ALDOA-DDX27-20-GOOR 20 (40 μL) 200 μL
ALDOA-DDX27-20-GOGO 20 (40 μL) 200 μL
ALDOA-DDX27-20-GOGR 20 (40 μL) 200 μL
ALDOA-DDX27-20-GOAQ 20 (40 μL) 200 μL
ALDOA-DDX27-20-GRRE 20 (40 μL) 200 μL
ALDOA-DDX27-20-GROR 20 (40 μL) 200 μL
ALDOA-DDX27-20-GRGO 20 (40 μL) 200 μL
ALDOA-DDX27-20-GRGR 20 (40 μL) 200 μL
ALDOA-DDX27-20-GRAQ 20 (40 μL) 200 μL
ALDOA-DDX27-20-AQRE 20 (40 μL) 200 μL
ALDOA-DDX27-20-AQOR 20 (40 μL) 200 μL
ALDOA-DDX27-20-AQGO 20 (40 μL) 200 μL
ALDOA-DDX27-20-AQGR 20 (40 μL) 200 μL
ALDOA-DDX27-20-AQAQ 20 (40 μL) 200 μL

ALDOA Gene Summary

This gene encodes a member of the class I fructose-bisphosphate aldolase protein family. The encoded protein is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Mutations in this gene have been associated with Glycogen Storage Disease XII, an autosomal recessive disorder associated with hemolytic anemia. Disruption of this gene also plays a role in the progression of multiple types of cancers. Related pseudogenes have been identified on chromosomes 3 and 10. [provided by RefSeq, Sep 2017]

Gene Name: Aldolase, Fructose-bisphosphate A

Chromosome: CHR16: 30064410 -30081741

Locus: 16p11.2

DDX27 Gene Summary

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein involved in the processing of 5.8S and 28S ribosomal RNAs. More specifically, the encoded protein localizes to the nucleolus, where it interacts with the PeBoW complex to ensure proper 3' end formation of 47S rRNA. [provided by RefSeq, Jan 2017]

Gene Name: DEAD-box Helicase 27

Chromosome: CHR20: 47835831 -47860614

Locus: 20q13.13

Gene Diseases

The ALDOA DDX27 Fusion has been associated with the following diseases:

Disease Name
Rectum Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.