ALDOA-DDX27 Fusion FISH Probe
The ALDOA-DDX27 Fusion FISH Probe is used to confirm a fusion of the ALDOA and DDX27 genes. The fusion of the ALDOA and DDX27 genes has been associated with Rectum Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ALDOA-DDX27-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| ALDOA-DDX27-20-RERE | 20 (40 μL) | 200 μL |
|
|
| ALDOA-DDX27-20-REOR | 20 (40 μL) | 200 μL |
|
|
| ALDOA-DDX27-20-REGO | 20 (40 μL) | 200 μL |
|
|
| ALDOA-DDX27-20-REGR | 20 (40 μL) | 200 μL |
|
|
| ALDOA-DDX27-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| ALDOA-DDX27-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| ALDOA-DDX27-20-OROR | 20 (40 μL) | 200 μL |
|
|
| ALDOA-DDX27-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| ALDOA-DDX27-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| ALDOA-DDX27-20-GORE | 20 (40 μL) | 200 μL |
|
|
| ALDOA-DDX27-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| ALDOA-DDX27-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| ALDOA-DDX27-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| ALDOA-DDX27-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| ALDOA-DDX27-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| ALDOA-DDX27-20-GROR | 20 (40 μL) | 200 μL |
|
|
| ALDOA-DDX27-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| ALDOA-DDX27-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| ALDOA-DDX27-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| ALDOA-DDX27-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| ALDOA-DDX27-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| ALDOA-DDX27-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| ALDOA-DDX27-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| ALDOA-DDX27-20-AQAQ | 20 (40 μL) | 200 μL |
|
ALDOA Gene Summary
This gene encodes a member of the class I fructose-bisphosphate aldolase protein family. The encoded protein is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Mutations in this gene have been associated with Glycogen Storage Disease XII, an autosomal recessive disorder associated with hemolytic anemia. Disruption of this gene also plays a role in the progression of multiple types of cancers. Related pseudogenes have been identified on chromosomes 3 and 10. [provided by RefSeq, Sep 2017]
Gene Name: Aldolase, Fructose-bisphosphate A
Chromosome: CHR16: 30064410 -30081741
Locus: 16p11.2
DDX27 Gene Summary
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein involved in the processing of 5.8S and 28S ribosomal RNAs. More specifically, the encoded protein localizes to the nucleolus, where it interacts with the PeBoW complex to ensure proper 3' end formation of 47S rRNA. [provided by RefSeq, Jan 2017]
Gene Name: DEAD-box Helicase 27
Chromosome: CHR20: 47835831 -47860614
Locus: 20q13.13
Gene Diseases
The ALDOA DDX27 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Rectum Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|