ALDOA-ARFGEF2 Fusion FISH Probe
The ALDOA-ARFGEF2 Fusion FISH Probe is used to confirm a fusion of the ALDOA and ARFGEF2 genes. The fusion of the ALDOA and ARFGEF2 genes has been associated with Thyroid Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ALDOA-ARFGEF2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ALDOA-ARFGEF2-20-RERE | 20 (40 μL) | 200 μL |
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| ALDOA-ARFGEF2-20-REOR | 20 (40 μL) | 200 μL |
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| ALDOA-ARFGEF2-20-REGO | 20 (40 μL) | 200 μL |
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| ALDOA-ARFGEF2-20-REGR | 20 (40 μL) | 200 μL |
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| ALDOA-ARFGEF2-20-REAQ | 20 (40 μL) | 200 μL |
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| ALDOA-ARFGEF2-20-ORRE | 20 (40 μL) | 200 μL |
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| ALDOA-ARFGEF2-20-OROR | 20 (40 μL) | 200 μL |
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| ALDOA-ARFGEF2-20-ORGO | 20 (40 μL) | 200 μL |
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| ALDOA-ARFGEF2-20-ORAQ | 20 (40 μL) | 200 μL |
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| ALDOA-ARFGEF2-20-GORE | 20 (40 μL) | 200 μL |
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| ALDOA-ARFGEF2-20-GOOR | 20 (40 μL) | 200 μL |
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| ALDOA-ARFGEF2-20-GOGO | 20 (40 μL) | 200 μL |
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| ALDOA-ARFGEF2-20-GOGR | 20 (40 μL) | 200 μL |
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| ALDOA-ARFGEF2-20-GOAQ | 20 (40 μL) | 200 μL |
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| ALDOA-ARFGEF2-20-GRRE | 20 (40 μL) | 200 μL |
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| ALDOA-ARFGEF2-20-GROR | 20 (40 μL) | 200 μL |
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| ALDOA-ARFGEF2-20-GRGO | 20 (40 μL) | 200 μL |
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| ALDOA-ARFGEF2-20-GRGR | 20 (40 μL) | 200 μL |
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| ALDOA-ARFGEF2-20-GRAQ | 20 (40 μL) | 200 μL |
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| ALDOA-ARFGEF2-20-AQRE | 20 (40 μL) | 200 μL |
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| ALDOA-ARFGEF2-20-AQOR | 20 (40 μL) | 200 μL |
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| ALDOA-ARFGEF2-20-AQGO | 20 (40 μL) | 200 μL |
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| ALDOA-ARFGEF2-20-AQGR | 20 (40 μL) | 200 μL |
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| ALDOA-ARFGEF2-20-AQAQ | 20 (40 μL) | 200 μL |
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ALDOA Gene Summary
This gene encodes a member of the class I fructose-bisphosphate aldolase protein family. The encoded protein is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Mutations in this gene have been associated with Glycogen Storage Disease XII, an autosomal recessive disorder associated with hemolytic anemia. Disruption of this gene also plays a role in the progression of multiple types of cancers. Related pseudogenes have been identified on chromosomes 3 and 10. [provided by RefSeq, Sep 2017]
Gene Name: Aldolase, Fructose-bisphosphate A
Chromosome: CHR16: 30064410 -30081741
Locus: 16p11.2
ARFGEF2 Gene Summary
ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP and is involved in Golgi transport. It contains a Sec7 domain, which may be responsible for its guanine-nucleotide exchange activity and also brefeldin A inhibition. [provided by RefSeq, Jul 2008]
Gene Name: ADP Ribosylation Factor Guanine Nucleotide Exchange Factor 2
Chromosome: CHR20: 47538274 -47653230
Locus: 20q13.13
Gene Diseases
The ALDOA ARFGEF2 Fusion has been associated with the following diseases:
| Disease Name |
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| Thyroid Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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