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ALDH7A1-PIP Fusion FISH Probe

The ALDH7A1-PIP Fusion FISH Probe is used to confirm a fusion of the ALDH7A1 and PIP genes. The fusion of the ALDH7A1 and PIP genes has been associated with Ovarian Serous Cystadenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ALDH7A1-PIP-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
ALDH7A1-PIP-20-RERE 20 (40 μL) 200 μL
ALDH7A1-PIP-20-REOR 20 (40 μL) 200 μL
ALDH7A1-PIP-20-REGO 20 (40 μL) 200 μL
ALDH7A1-PIP-20-REGR 20 (40 μL) 200 μL
ALDH7A1-PIP-20-REAQ 20 (40 μL) 200 μL
ALDH7A1-PIP-20-ORRE 20 (40 μL) 200 μL
ALDH7A1-PIP-20-OROR 20 (40 μL) 200 μL
ALDH7A1-PIP-20-ORGO 20 (40 μL) 200 μL
ALDH7A1-PIP-20-ORAQ 20 (40 μL) 200 μL
ALDH7A1-PIP-20-GORE 20 (40 μL) 200 μL
ALDH7A1-PIP-20-GOOR 20 (40 μL) 200 μL
ALDH7A1-PIP-20-GOGO 20 (40 μL) 200 μL
ALDH7A1-PIP-20-GOGR 20 (40 μL) 200 μL
ALDH7A1-PIP-20-GOAQ 20 (40 μL) 200 μL
ALDH7A1-PIP-20-GRRE 20 (40 μL) 200 μL
ALDH7A1-PIP-20-GROR 20 (40 μL) 200 μL
ALDH7A1-PIP-20-GRGO 20 (40 μL) 200 μL
ALDH7A1-PIP-20-GRGR 20 (40 μL) 200 μL
ALDH7A1-PIP-20-GRAQ 20 (40 μL) 200 μL
ALDH7A1-PIP-20-AQRE 20 (40 μL) 200 μL
ALDH7A1-PIP-20-AQOR 20 (40 μL) 200 μL
ALDH7A1-PIP-20-AQGO 20 (40 μL) 200 μL
ALDH7A1-PIP-20-AQGR 20 (40 μL) 200 μL
ALDH7A1-PIP-20-AQAQ 20 (40 μL) 200 μL

ALDH7A1 Gene Summary

The protein encoded by this gene is a member of subfamily 7 in the aldehyde dehydrogenase gene family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This particular member has homology to a previously described protein from the green garden pea, the 26g pea turgor protein. It is also involved in lysine catabolism that is known to occur in the mitochondrial matrix. Recent reports show that this protein is found both in the cytosol and the mitochondria, and the two forms likely arise from the use of alternative translation initiation sites. An additional variant encoding a different isoform has also been found for this gene. Mutations in this gene are associated with pyridoxine-dependent epilepsy. Several related pseudogenes have also been identified. [provided by RefSeq, Jan 2011]

Gene Name: Aldehyde Dehydrogenase 7 Family Member A1

Chromosome: CHR5: 125877532 -125931082

Locus: 5q23.2

PIP Gene Summary

The Prolactin Induced Protein (PIP) gene is located on chr7 :142829173-142836834 at 7q34.

Gene Name: Prolactin Induced Protein

Chromosome: CHR7: 142829173 -142836834

Locus: 7q34

Gene Diseases

The ALDH7A1 PIP Fusion has been associated with the following diseases:

Disease Name
Ovarian Serous Cystadenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.