ALDH3A1-MYH9 Fusion FISH Probe
The ALDH3A1-MYH9 Fusion FISH Probe is used to confirm a fusion of the ALDH3A1 and MYH9 genes. The fusion of the ALDH3A1 and MYH9 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ALDH3A1-MYH9-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ALDH3A1-MYH9-20-RERE | 20 (40 μL) | 200 μL |
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| ALDH3A1-MYH9-20-REOR | 20 (40 μL) | 200 μL |
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| ALDH3A1-MYH9-20-REGO | 20 (40 μL) | 200 μL |
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| ALDH3A1-MYH9-20-REGR | 20 (40 μL) | 200 μL |
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| ALDH3A1-MYH9-20-REAQ | 20 (40 μL) | 200 μL |
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| ALDH3A1-MYH9-20-ORRE | 20 (40 μL) | 200 μL |
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| ALDH3A1-MYH9-20-OROR | 20 (40 μL) | 200 μL |
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| ALDH3A1-MYH9-20-ORGO | 20 (40 μL) | 200 μL |
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| ALDH3A1-MYH9-20-ORAQ | 20 (40 μL) | 200 μL |
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| ALDH3A1-MYH9-20-GORE | 20 (40 μL) | 200 μL |
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| ALDH3A1-MYH9-20-GOOR | 20 (40 μL) | 200 μL |
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| ALDH3A1-MYH9-20-GOGO | 20 (40 μL) | 200 μL |
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| ALDH3A1-MYH9-20-GOGR | 20 (40 μL) | 200 μL |
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| ALDH3A1-MYH9-20-GOAQ | 20 (40 μL) | 200 μL |
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| ALDH3A1-MYH9-20-GRRE | 20 (40 μL) | 200 μL |
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| ALDH3A1-MYH9-20-GROR | 20 (40 μL) | 200 μL |
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| ALDH3A1-MYH9-20-GRGO | 20 (40 μL) | 200 μL |
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| ALDH3A1-MYH9-20-GRGR | 20 (40 μL) | 200 μL |
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| ALDH3A1-MYH9-20-GRAQ | 20 (40 μL) | 200 μL |
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| ALDH3A1-MYH9-20-AQRE | 20 (40 μL) | 200 μL |
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| ALDH3A1-MYH9-20-AQOR | 20 (40 μL) | 200 μL |
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| ALDH3A1-MYH9-20-AQGO | 20 (40 μL) | 200 μL |
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| ALDH3A1-MYH9-20-AQGR | 20 (40 μL) | 200 μL |
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| ALDH3A1-MYH9-20-AQAQ | 20 (40 μL) | 200 μL |
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ALDH3A1 Gene Summary
Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008]
Gene Name: Aldehyde Dehydrogenase 3 Family Member A1
Chromosome: CHR17: 19641297 -19651746
Locus: 17p11.2
MYH9 Gene Summary
This gene encodes a conventional non-muscle myosin; this protein should not be confused with the unconventional myosin-9a or 9b (MYO9A or MYO9B). The encoded protein is a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain which is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in this gene have been associated with non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness. [provided by RefSeq, Dec 2011]
Gene Name: Myosin Heavy Chain 9
Chromosome: CHR22: 36677322 -36784063
Locus: 22q12.3
Gene Diseases
The ALDH3A1 MYH9 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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