ALCAM-SH3KBP1 Fusion FISH Probe
The ALCAM-SH3KBP1 Fusion FISH Probe is used to confirm a fusion of the ALCAM and SH3KBP1 genes. The fusion of the ALCAM and SH3KBP1 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ALCAM-SH3KBP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ALCAM-SH3KBP1-20-RERE | 20 (40 μL) | 200 μL |
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| ALCAM-SH3KBP1-20-REOR | 20 (40 μL) | 200 μL |
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| ALCAM-SH3KBP1-20-REGO | 20 (40 μL) | 200 μL |
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| ALCAM-SH3KBP1-20-REGR | 20 (40 μL) | 200 μL |
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| ALCAM-SH3KBP1-20-REAQ | 20 (40 μL) | 200 μL |
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| ALCAM-SH3KBP1-20-ORRE | 20 (40 μL) | 200 μL |
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| ALCAM-SH3KBP1-20-OROR | 20 (40 μL) | 200 μL |
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| ALCAM-SH3KBP1-20-ORGO | 20 (40 μL) | 200 μL |
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| ALCAM-SH3KBP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ALCAM-SH3KBP1-20-GORE | 20 (40 μL) | 200 μL |
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| ALCAM-SH3KBP1-20-GOOR | 20 (40 μL) | 200 μL |
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| ALCAM-SH3KBP1-20-GOGO | 20 (40 μL) | 200 μL |
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| ALCAM-SH3KBP1-20-GOGR | 20 (40 μL) | 200 μL |
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| ALCAM-SH3KBP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ALCAM-SH3KBP1-20-GRRE | 20 (40 μL) | 200 μL |
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| ALCAM-SH3KBP1-20-GROR | 20 (40 μL) | 200 μL |
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| ALCAM-SH3KBP1-20-GRGO | 20 (40 μL) | 200 μL |
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| ALCAM-SH3KBP1-20-GRGR | 20 (40 μL) | 200 μL |
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| ALCAM-SH3KBP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ALCAM-SH3KBP1-20-AQRE | 20 (40 μL) | 200 μL |
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| ALCAM-SH3KBP1-20-AQOR | 20 (40 μL) | 200 μL |
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| ALCAM-SH3KBP1-20-AQGO | 20 (40 μL) | 200 μL |
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| ALCAM-SH3KBP1-20-AQGR | 20 (40 μL) | 200 μL |
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| ALCAM-SH3KBP1-20-AQAQ | 20 (40 μL) | 200 μL |
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ALCAM Gene Summary
This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. This protein binds to T-cell differentiation antigene CD6, and is implicated in the processes of cell adhesion and migration. Multiple alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Aug 2011]
Gene Name: Activated Leukocyte Cell Adhesion Molecule
Chromosome: CHR3: 105085556 -105295757
Locus: 3q13.11
SH3KBP1 Gene Summary
This gene encodes an adapter protein that contains one or more N-terminal Src homology domains, a proline rich region and a C-terminal coiled-coil domain. The encoded protein facilitates protein-protein interactions and has been implicated in numerous cellular processes including apoptosis, cytoskeletal rearrangement, cell adhesion and in the regulation of clathrin-dependent endocytosis. Alternate splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2017]
Gene Name: SH3 Domain Containing Kinase Binding Protein 1
Chromosome: CHRX: 19552082 -19905744
Locus: Xp22.12
Gene Diseases
The ALCAM SH3KBP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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