ALCAM-EIF2A Fusion FISH Probe
The ALCAM-EIF2A Fusion FISH Probe is used to confirm a fusion of the ALCAM and EIF2A genes. The fusion of the ALCAM and EIF2A genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ALCAM-EIF2A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ALCAM-EIF2A-20-RERE | 20 (40 μL) | 200 μL |
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| ALCAM-EIF2A-20-REOR | 20 (40 μL) | 200 μL |
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| ALCAM-EIF2A-20-REGO | 20 (40 μL) | 200 μL |
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| ALCAM-EIF2A-20-REGR | 20 (40 μL) | 200 μL |
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| ALCAM-EIF2A-20-REAQ | 20 (40 μL) | 200 μL |
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| ALCAM-EIF2A-20-ORRE | 20 (40 μL) | 200 μL |
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| ALCAM-EIF2A-20-OROR | 20 (40 μL) | 200 μL |
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| ALCAM-EIF2A-20-ORGO | 20 (40 μL) | 200 μL |
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| ALCAM-EIF2A-20-ORAQ | 20 (40 μL) | 200 μL |
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| ALCAM-EIF2A-20-GORE | 20 (40 μL) | 200 μL |
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| ALCAM-EIF2A-20-GOOR | 20 (40 μL) | 200 μL |
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| ALCAM-EIF2A-20-GOGO | 20 (40 μL) | 200 μL |
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| ALCAM-EIF2A-20-GOGR | 20 (40 μL) | 200 μL |
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| ALCAM-EIF2A-20-GOAQ | 20 (40 μL) | 200 μL |
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| ALCAM-EIF2A-20-GRRE | 20 (40 μL) | 200 μL |
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| ALCAM-EIF2A-20-GROR | 20 (40 μL) | 200 μL |
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| ALCAM-EIF2A-20-GRGO | 20 (40 μL) | 200 μL |
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| ALCAM-EIF2A-20-GRGR | 20 (40 μL) | 200 μL |
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| ALCAM-EIF2A-20-GRAQ | 20 (40 μL) | 200 μL |
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| ALCAM-EIF2A-20-AQRE | 20 (40 μL) | 200 μL |
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| ALCAM-EIF2A-20-AQOR | 20 (40 μL) | 200 μL |
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| ALCAM-EIF2A-20-AQGO | 20 (40 μL) | 200 μL |
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| ALCAM-EIF2A-20-AQGR | 20 (40 μL) | 200 μL |
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| ALCAM-EIF2A-20-AQAQ | 20 (40 μL) | 200 μL |
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ALCAM Gene Summary
This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. This protein binds to T-cell differentiation antigene CD6, and is implicated in the processes of cell adhesion and migration. Multiple alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Aug 2011]
Gene Name: Activated Leukocyte Cell Adhesion Molecule
Chromosome: CHR3: 105085556 -105295757
Locus: 3q13.11
EIF2A Gene Summary
This gene encodes a eukaryotic translation initiation factor that catalyzes the formation of puromycin-sensitive 80 S preinitiation complexes and the poly(U)-directed synthesis of polyphenylalanine at low concentrations of Mg2+. This gene should not be confused with eIF2-alpha (EIF2S1, Gene ID: 1965), the alpha subunit of the eIF2 translation initiation complex. Although both of these proteins function in binding initiator tRNA to the 40 S ribosomal subunit, the encoded protein does so in a codon-dependent manner, whereas eIF2 complex requires GTP. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]
Gene Name: Eukaryotic Translation Initiation Factor 2A
Chromosome: CHR3: 150264573 -150303803
Locus: 3q25.1
Gene Diseases
The ALCAM EIF2A Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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