ALB-SEC63 Fusion FISH Probe
The ALB-SEC63 Fusion FISH Probe is used to confirm a fusion of the ALB and SEC63 genes. The fusion of the ALB and SEC63 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ALB-SEC63-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ALB-SEC63-20-RERE | 20 (40 μL) | 200 μL |
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| ALB-SEC63-20-REOR | 20 (40 μL) | 200 μL |
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| ALB-SEC63-20-REGO | 20 (40 μL) | 200 μL |
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| ALB-SEC63-20-REGR | 20 (40 μL) | 200 μL |
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| ALB-SEC63-20-REAQ | 20 (40 μL) | 200 μL |
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| ALB-SEC63-20-ORRE | 20 (40 μL) | 200 μL |
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| ALB-SEC63-20-OROR | 20 (40 μL) | 200 μL |
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| ALB-SEC63-20-ORGO | 20 (40 μL) | 200 μL |
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| ALB-SEC63-20-ORAQ | 20 (40 μL) | 200 μL |
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| ALB-SEC63-20-GORE | 20 (40 μL) | 200 μL |
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| ALB-SEC63-20-GOOR | 20 (40 μL) | 200 μL |
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| ALB-SEC63-20-GOGO | 20 (40 μL) | 200 μL |
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| ALB-SEC63-20-GOGR | 20 (40 μL) | 200 μL |
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| ALB-SEC63-20-GOAQ | 20 (40 μL) | 200 μL |
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| ALB-SEC63-20-GRRE | 20 (40 μL) | 200 μL |
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| ALB-SEC63-20-GROR | 20 (40 μL) | 200 μL |
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| ALB-SEC63-20-GRGO | 20 (40 μL) | 200 μL |
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| ALB-SEC63-20-GRGR | 20 (40 μL) | 200 μL |
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| ALB-SEC63-20-GRAQ | 20 (40 μL) | 200 μL |
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| ALB-SEC63-20-AQRE | 20 (40 μL) | 200 μL |
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| ALB-SEC63-20-AQOR | 20 (40 μL) | 200 μL |
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| ALB-SEC63-20-AQGO | 20 (40 μL) | 200 μL |
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| ALB-SEC63-20-AQGR | 20 (40 μL) | 200 μL |
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| ALB-SEC63-20-AQAQ | 20 (40 μL) | 200 μL |
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ALB Gene Summary
This gene encodes the most abundant protein in human blood. This protein functions in the regulation of blood plasma colloid osmotic pressure and acts as a carrier protein for a wide range of endogenous molecules including hormones, fatty acids, and metabolites, as well as exogenous drugs. Additionally, this protein exhibits an esterase-like activity with broad substrate specificity. The encoded preproprotein is proteolytically processed to generate the mature protein. A peptide derived from this protein, EPI-X4, is an endogenous inhibitor of the CXCR4 chemokine receptor. [provided by RefSeq, Jul 2016]
Gene Name: Albumin
Chromosome: CHR4: 74269971 -74287129
Locus: 4q13.3
SEC63 Gene Summary
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. [provided by RefSeq, Jul 2008]
Gene Name: SEC63 Homolog, Protein Translocation Regulator
Chromosome: CHR6: 108188959 -108279482
Locus: 6q21
Gene Diseases
The ALB SEC63 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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