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AKT3-PTPRR Fusion FISH Probe

The AKT3-PTPRR Fusion FISH Probe is used to confirm a fusion of the AKT3 and PTPRR genes. The fusion of the AKT3 and PTPRR genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
AKT3-PTPRR-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
AKT3-PTPRR-20-RERE 20 (40 μL) 200 μL
AKT3-PTPRR-20-REOR 20 (40 μL) 200 μL
AKT3-PTPRR-20-REGO 20 (40 μL) 200 μL
AKT3-PTPRR-20-REGR 20 (40 μL) 200 μL
AKT3-PTPRR-20-REAQ 20 (40 μL) 200 μL
AKT3-PTPRR-20-ORRE 20 (40 μL) 200 μL
AKT3-PTPRR-20-OROR 20 (40 μL) 200 μL
AKT3-PTPRR-20-ORGO 20 (40 μL) 200 μL
AKT3-PTPRR-20-ORAQ 20 (40 μL) 200 μL
AKT3-PTPRR-20-GORE 20 (40 μL) 200 μL
AKT3-PTPRR-20-GOOR 20 (40 μL) 200 μL
AKT3-PTPRR-20-GOGO 20 (40 μL) 200 μL
AKT3-PTPRR-20-GOGR 20 (40 μL) 200 μL
AKT3-PTPRR-20-GOAQ 20 (40 μL) 200 μL
AKT3-PTPRR-20-GRRE 20 (40 μL) 200 μL
AKT3-PTPRR-20-GROR 20 (40 μL) 200 μL
AKT3-PTPRR-20-GRGO 20 (40 μL) 200 μL
AKT3-PTPRR-20-GRGR 20 (40 μL) 200 μL
AKT3-PTPRR-20-GRAQ 20 (40 μL) 200 μL
AKT3-PTPRR-20-AQRE 20 (40 μL) 200 μL
AKT3-PTPRR-20-AQOR 20 (40 μL) 200 μL
AKT3-PTPRR-20-AQGO 20 (40 μL) 200 μL
AKT3-PTPRR-20-AQGR 20 (40 μL) 200 μL
AKT3-PTPRR-20-AQAQ 20 (40 μL) 200 μL

PTPRR Gene Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. Silencing of this gene has been associated with colorectal cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares a symbol (PTPRQ) with another gene, protein tyrosine phosphatase, receptor type, Q (GeneID 374462), which is also located on chromosome 12. [provided by RefSeq, May 2011]

Gene Name: Protein Tyrosine Phosphatase, Receptor Type R

Chromosome: CHR12: 71031852 -71314584

Locus: 12q15

AKT3 Gene Summary

The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1). Alternatively splice transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]

Gene Name: AKT Serine/threonine Kinase 3

Chromosome: CHR1: 243651534 -244006584

Locus: 1q43-q44

Gene Diseases

The AKT3 PTPRR Fusion has been associated with the following diseases:

Disease Name
Skin Cutaneous Melanoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.