AKT2-YIF1B Fusion FISH Probe
The AKT2-YIF1B Fusion FISH Probe is used to confirm a fusion of the AKT2 and YIF1B genes. The fusion of the AKT2 and YIF1B genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| AKT2-YIF1B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| AKT2-YIF1B-20-RERE | 20 (40 μL) | 200 μL |
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| AKT2-YIF1B-20-REOR | 20 (40 μL) | 200 μL |
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| AKT2-YIF1B-20-REGO | 20 (40 μL) | 200 μL |
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| AKT2-YIF1B-20-REGR | 20 (40 μL) | 200 μL |
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| AKT2-YIF1B-20-REAQ | 20 (40 μL) | 200 μL |
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| AKT2-YIF1B-20-ORRE | 20 (40 μL) | 200 μL |
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| AKT2-YIF1B-20-OROR | 20 (40 μL) | 200 μL |
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| AKT2-YIF1B-20-ORGO | 20 (40 μL) | 200 μL |
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| AKT2-YIF1B-20-ORAQ | 20 (40 μL) | 200 μL |
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| AKT2-YIF1B-20-GORE | 20 (40 μL) | 200 μL |
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| AKT2-YIF1B-20-GOOR | 20 (40 μL) | 200 μL |
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| AKT2-YIF1B-20-GOGO | 20 (40 μL) | 200 μL |
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| AKT2-YIF1B-20-GOGR | 20 (40 μL) | 200 μL |
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| AKT2-YIF1B-20-GOAQ | 20 (40 μL) | 200 μL |
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| AKT2-YIF1B-20-GRRE | 20 (40 μL) | 200 μL |
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| AKT2-YIF1B-20-GROR | 20 (40 μL) | 200 μL |
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| AKT2-YIF1B-20-GRGO | 20 (40 μL) | 200 μL |
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| AKT2-YIF1B-20-GRGR | 20 (40 μL) | 200 μL |
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| AKT2-YIF1B-20-GRAQ | 20 (40 μL) | 200 μL |
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| AKT2-YIF1B-20-AQRE | 20 (40 μL) | 200 μL |
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| AKT2-YIF1B-20-AQOR | 20 (40 μL) | 200 μL |
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| AKT2-YIF1B-20-AQGO | 20 (40 μL) | 200 μL |
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| AKT2-YIF1B-20-AQGR | 20 (40 μL) | 200 μL |
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| AKT2-YIF1B-20-AQAQ | 20 (40 μL) | 200 μL |
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AKT2 Gene Summary
This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins. [provided by RefSeq, Jul 2008]
Gene Name: AKT Serine/threonine Kinase 2
Chromosome: CHR19: 40736223 -40791302
Locus: 19q13.2
YIF1B Gene Summary
The Yip1 Interacting Factor Homolog B, Membrane Trafficking Protein (YIF1B) gene is located on chr19 :38794199-38806606 at 19q13.2.
Gene Name: Yip1 Interacting Factor Homolog B, Membrane Trafficking Protein
Chromosome: CHR19: 38794199 -38806606
Locus: 19q13.2
Gene Diseases
The AKT2 YIF1B Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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