AKAP9-RUNX1 Fusion FISH Probe
The AKAP9-RUNX1 Fusion FISH Probe is used to confirm a fusion of the AKAP9 and RUNX1 genes. The fusion of the AKAP9 and RUNX1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| AKAP9-RUNX1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| AKAP9-RUNX1-20-RERE | 20 (40 μL) | 200 μL |
|
|
| AKAP9-RUNX1-20-REOR | 20 (40 μL) | 200 μL |
|
|
| AKAP9-RUNX1-20-REGO | 20 (40 μL) | 200 μL |
|
|
| AKAP9-RUNX1-20-REGR | 20 (40 μL) | 200 μL |
|
|
| AKAP9-RUNX1-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| AKAP9-RUNX1-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| AKAP9-RUNX1-20-OROR | 20 (40 μL) | 200 μL |
|
|
| AKAP9-RUNX1-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| AKAP9-RUNX1-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| AKAP9-RUNX1-20-GORE | 20 (40 μL) | 200 μL |
|
|
| AKAP9-RUNX1-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| AKAP9-RUNX1-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| AKAP9-RUNX1-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| AKAP9-RUNX1-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| AKAP9-RUNX1-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| AKAP9-RUNX1-20-GROR | 20 (40 μL) | 200 μL |
|
|
| AKAP9-RUNX1-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| AKAP9-RUNX1-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| AKAP9-RUNX1-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| AKAP9-RUNX1-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| AKAP9-RUNX1-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| AKAP9-RUNX1-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| AKAP9-RUNX1-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| AKAP9-RUNX1-20-AQAQ | 20 (40 μL) | 200 μL |
|
RUNX1 Gene Summary
Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Runt Related Transcription Factor 1
Chromosome: CHR21: 36160097 -36421595
Locus: 21q22.12
AKAP9 Gene Summary
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternate splicing of this gene results in at least two isoforms that localize to the centrosome and the Golgi apparatus, and interact with numerous signaling proteins from multiple signal transduction pathways. These signaling proteins include type II protein kinase A, serine/threonine kinase protein kinase N, protein phosphatase 1, protein phosphatase 2a, protein kinase C-epsilon and phosphodiesterase 4D3. [provided by RefSeq, Aug 2008]
Gene Name: A-kinase Anchoring Protein 9
Chromosome: CHR7: 91570188 -91739987
Locus: 7q21.2
Gene Diseases
The AKAP9 RUNX1 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|