AKAP8-CALR3 Fusion FISH Probe
The AKAP8-CALR3 Fusion FISH Probe is used to confirm a fusion of the AKAP8 and CALR3 genes. The fusion of the AKAP8 and CALR3 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| AKAP8-CALR3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| AKAP8-CALR3-20-RERE | 20 (40 μL) | 200 μL |
|
|
| AKAP8-CALR3-20-REOR | 20 (40 μL) | 200 μL |
|
|
| AKAP8-CALR3-20-REGO | 20 (40 μL) | 200 μL |
|
|
| AKAP8-CALR3-20-REGR | 20 (40 μL) | 200 μL |
|
|
| AKAP8-CALR3-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| AKAP8-CALR3-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| AKAP8-CALR3-20-OROR | 20 (40 μL) | 200 μL |
|
|
| AKAP8-CALR3-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| AKAP8-CALR3-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| AKAP8-CALR3-20-GORE | 20 (40 μL) | 200 μL |
|
|
| AKAP8-CALR3-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| AKAP8-CALR3-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| AKAP8-CALR3-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| AKAP8-CALR3-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| AKAP8-CALR3-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| AKAP8-CALR3-20-GROR | 20 (40 μL) | 200 μL |
|
|
| AKAP8-CALR3-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| AKAP8-CALR3-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| AKAP8-CALR3-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| AKAP8-CALR3-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| AKAP8-CALR3-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| AKAP8-CALR3-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| AKAP8-CALR3-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| AKAP8-CALR3-20-AQAQ | 20 (40 μL) | 200 μL |
|
AKAP8 Gene Summary
This gene encodes a member of the A-kinase anchor protein family. A-kinase anchor proteins are scaffold proteins that contain a binding domain for the RI/RII subunit of protein kinase A (PKA) and recruit PKA and other signaling molecules to specific subcellular locations. This gene encodes a nuclear A-kinase anchor protein that binds to the RII alpha subunit of PKA and may play a role in chromosome condensation during mitosis by targeting PKA and the condensin complex to chromatin. A pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, May 2011]
Gene Name: A-kinase Anchoring Protein 8
Chromosome: CHR19: 15464331 -15490612
Locus: 19p13.12
CALR3 Gene Summary
The protein encoded by this gene belongs to the calreticulin family, members of which are calcium-binding chaperones localized mainly in the endoplasmic reticulum. This protein is also localized to the endoplasmic reticulum lumen, however, its capacity for calcium-binding may be absent or much lower than other family members. This gene is specifically expressed in the testis, and may be required for sperm fertility. Mutation in this gene has been associated with familial hypertrophic cardiomyopathy. [provided by RefSeq, Dec 2011]
Gene Name: Calreticulin 3
Chromosome: CHR19: 16589874 -16607003
Locus: 19p13.11
Gene Diseases
The AKAP8 CALR3 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|