AKAP6-PRKD1 Fusion FISH Probe
The AKAP6-PRKD1 Fusion FISH Probe is used to confirm a fusion of the AKAP6 and PRKD1 genes. The fusion of the AKAP6 and PRKD1 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| AKAP6-PRKD1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| AKAP6-PRKD1-20-RERE | 20 (40 μL) | 200 μL |
|
|
| AKAP6-PRKD1-20-REOR | 20 (40 μL) | 200 μL |
|
|
| AKAP6-PRKD1-20-REGO | 20 (40 μL) | 200 μL |
|
|
| AKAP6-PRKD1-20-REGR | 20 (40 μL) | 200 μL |
|
|
| AKAP6-PRKD1-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| AKAP6-PRKD1-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| AKAP6-PRKD1-20-OROR | 20 (40 μL) | 200 μL |
|
|
| AKAP6-PRKD1-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| AKAP6-PRKD1-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| AKAP6-PRKD1-20-GORE | 20 (40 μL) | 200 μL |
|
|
| AKAP6-PRKD1-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| AKAP6-PRKD1-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| AKAP6-PRKD1-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| AKAP6-PRKD1-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| AKAP6-PRKD1-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| AKAP6-PRKD1-20-GROR | 20 (40 μL) | 200 μL |
|
|
| AKAP6-PRKD1-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| AKAP6-PRKD1-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| AKAP6-PRKD1-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| AKAP6-PRKD1-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| AKAP6-PRKD1-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| AKAP6-PRKD1-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| AKAP6-PRKD1-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| AKAP6-PRKD1-20-AQAQ | 20 (40 μL) | 200 μL |
|
PRKD1 Gene Summary
The protein encoded by this gene is a serine/threonine protein kinase involved in many cellular processes, including Golgi body membrane integrity and transport, cell migration and differentiation, MAPK8/JNK1 and Ras pathway signaling, MAPK1/3 (ERK1/2) pathway signaling, cell survival, and regulation of cell shape and adhesion. [provided by RefSeq, Jan 2017]
Gene Name: Protein Kinase D1
Chromosome: CHR14: 30045686 -30396899
Locus: 14q12
AKAP6 Gene Summary
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is highly expressed in various brain regions and cardiac and skeletal muscle. It is specifically localized to the sarcoplasmic reticulum and nuclear membrane, and is involved in anchoring PKA to the nuclear membrane or sarcoplasmic reticulum. [provided by RefSeq, Jul 2008]
Gene Name: A-kinase Anchoring Protein 6
Chromosome: CHR14: 32798478 -33302268
Locus: 14q12
Gene Diseases
The AKAP6 PRKD1 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|