AKAP6-EGLN3 Fusion FISH Probe
The AKAP6-EGLN3 Fusion FISH Probe is used to confirm a fusion of the AKAP6 and EGLN3 genes. The fusion of the AKAP6 and EGLN3 genes has been associated with Glioblastoma Multiforme. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| AKAP6-EGLN3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| AKAP6-EGLN3-20-RERE | 20 (40 μL) | 200 μL |
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| AKAP6-EGLN3-20-REOR | 20 (40 μL) | 200 μL |
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| AKAP6-EGLN3-20-REGO | 20 (40 μL) | 200 μL |
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| AKAP6-EGLN3-20-REGR | 20 (40 μL) | 200 μL |
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| AKAP6-EGLN3-20-REAQ | 20 (40 μL) | 200 μL |
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| AKAP6-EGLN3-20-ORRE | 20 (40 μL) | 200 μL |
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| AKAP6-EGLN3-20-OROR | 20 (40 μL) | 200 μL |
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| AKAP6-EGLN3-20-ORGO | 20 (40 μL) | 200 μL |
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| AKAP6-EGLN3-20-ORAQ | 20 (40 μL) | 200 μL |
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| AKAP6-EGLN3-20-GORE | 20 (40 μL) | 200 μL |
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| AKAP6-EGLN3-20-GOOR | 20 (40 μL) | 200 μL |
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| AKAP6-EGLN3-20-GOGO | 20 (40 μL) | 200 μL |
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| AKAP6-EGLN3-20-GOGR | 20 (40 μL) | 200 μL |
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| AKAP6-EGLN3-20-GOAQ | 20 (40 μL) | 200 μL |
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| AKAP6-EGLN3-20-GRRE | 20 (40 μL) | 200 μL |
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| AKAP6-EGLN3-20-GROR | 20 (40 μL) | 200 μL |
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| AKAP6-EGLN3-20-GRGO | 20 (40 μL) | 200 μL |
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| AKAP6-EGLN3-20-GRGR | 20 (40 μL) | 200 μL |
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| AKAP6-EGLN3-20-GRAQ | 20 (40 μL) | 200 μL |
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| AKAP6-EGLN3-20-AQRE | 20 (40 μL) | 200 μL |
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| AKAP6-EGLN3-20-AQOR | 20 (40 μL) | 200 μL |
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| AKAP6-EGLN3-20-AQGO | 20 (40 μL) | 200 μL |
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| AKAP6-EGLN3-20-AQGR | 20 (40 μL) | 200 μL |
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| AKAP6-EGLN3-20-AQAQ | 20 (40 μL) | 200 μL |
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AKAP6 Gene Summary
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is highly expressed in various brain regions and cardiac and skeletal muscle. It is specifically localized to the sarcoplasmic reticulum and nuclear membrane, and is involved in anchoring PKA to the nuclear membrane or sarcoplasmic reticulum. [provided by RefSeq, Jul 2008]
Gene Name: A-kinase Anchoring Protein 6
Chromosome: CHR14: 32798478 -33302268
Locus: 14q12
EGLN3 Gene Summary
The Egl-9 Family Hypoxia Inducible Factor 3 (EGLN3) gene is located on chr14 :34393420-34420284 at 14q13.1.
Gene Name: Egl-9 Family Hypoxia Inducible Factor 3
Chromosome: CHR14: 34393420 -34420284
Locus: 14q13.1
Gene Diseases
The AKAP6 EGLN3 Fusion has been associated with the following diseases:
| Disease Name |
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| Glioblastoma Multiforme |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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