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AKAP6-EGLN3 Fusion FISH Probe

The AKAP6-EGLN3 Fusion FISH Probe is used to confirm a fusion of the AKAP6 and EGLN3 genes. The fusion of the AKAP6 and EGLN3 genes has been associated with Glioblastoma Multiforme. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
AKAP6-EGLN3-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
AKAP6-EGLN3-20-RERE 20 (40 μL) 200 μL
AKAP6-EGLN3-20-REOR 20 (40 μL) 200 μL
AKAP6-EGLN3-20-REGO 20 (40 μL) 200 μL
AKAP6-EGLN3-20-REGR 20 (40 μL) 200 μL
AKAP6-EGLN3-20-REAQ 20 (40 μL) 200 μL
AKAP6-EGLN3-20-ORRE 20 (40 μL) 200 μL
AKAP6-EGLN3-20-OROR 20 (40 μL) 200 μL
AKAP6-EGLN3-20-ORGO 20 (40 μL) 200 μL
AKAP6-EGLN3-20-ORAQ 20 (40 μL) 200 μL
AKAP6-EGLN3-20-GORE 20 (40 μL) 200 μL
AKAP6-EGLN3-20-GOOR 20 (40 μL) 200 μL
AKAP6-EGLN3-20-GOGO 20 (40 μL) 200 μL
AKAP6-EGLN3-20-GOGR 20 (40 μL) 200 μL
AKAP6-EGLN3-20-GOAQ 20 (40 μL) 200 μL
AKAP6-EGLN3-20-GRRE 20 (40 μL) 200 μL
AKAP6-EGLN3-20-GROR 20 (40 μL) 200 μL
AKAP6-EGLN3-20-GRGO 20 (40 μL) 200 μL
AKAP6-EGLN3-20-GRGR 20 (40 μL) 200 μL
AKAP6-EGLN3-20-GRAQ 20 (40 μL) 200 μL
AKAP6-EGLN3-20-AQRE 20 (40 μL) 200 μL
AKAP6-EGLN3-20-AQOR 20 (40 μL) 200 μL
AKAP6-EGLN3-20-AQGO 20 (40 μL) 200 μL
AKAP6-EGLN3-20-AQGR 20 (40 μL) 200 μL
AKAP6-EGLN3-20-AQAQ 20 (40 μL) 200 μL

AKAP6 Gene Summary

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is highly expressed in various brain regions and cardiac and skeletal muscle. It is specifically localized to the sarcoplasmic reticulum and nuclear membrane, and is involved in anchoring PKA to the nuclear membrane or sarcoplasmic reticulum. [provided by RefSeq, Jul 2008]

Gene Name: A-kinase Anchoring Protein 6

Chromosome: CHR14: 32798478 -33302268

Locus: 14q12

EGLN3 Gene Summary

The Egl-9 Family Hypoxia Inducible Factor 3 (EGLN3) gene is located on chr14 :34393420-34420284 at 14q13.1.

Gene Name: Egl-9 Family Hypoxia Inducible Factor 3

Chromosome: CHR14: 34393420 -34420284

Locus: 14q13.1

Gene Diseases

The AKAP6 EGLN3 Fusion has been associated with the following diseases:

Disease Name
Glioblastoma Multiforme

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.