AK5-USP33 Fusion FISH Probe
The AK5-USP33 Fusion FISH Probe is used to confirm a fusion of the AK5 and USP33 genes. The fusion of the AK5 and USP33 genes has been associated with Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| AK5-USP33-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| AK5-USP33-20-RERE | 20 (40 μL) | 200 μL |
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| AK5-USP33-20-REOR | 20 (40 μL) | 200 μL |
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| AK5-USP33-20-REGO | 20 (40 μL) | 200 μL |
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| AK5-USP33-20-REGR | 20 (40 μL) | 200 μL |
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| AK5-USP33-20-REAQ | 20 (40 μL) | 200 μL |
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| AK5-USP33-20-ORRE | 20 (40 μL) | 200 μL |
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| AK5-USP33-20-OROR | 20 (40 μL) | 200 μL |
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| AK5-USP33-20-ORGO | 20 (40 μL) | 200 μL |
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| AK5-USP33-20-ORAQ | 20 (40 μL) | 200 μL |
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| AK5-USP33-20-GORE | 20 (40 μL) | 200 μL |
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| AK5-USP33-20-GOOR | 20 (40 μL) | 200 μL |
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| AK5-USP33-20-GOGO | 20 (40 μL) | 200 μL |
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| AK5-USP33-20-GOGR | 20 (40 μL) | 200 μL |
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| AK5-USP33-20-GOAQ | 20 (40 μL) | 200 μL |
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| AK5-USP33-20-GRRE | 20 (40 μL) | 200 μL |
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| AK5-USP33-20-GROR | 20 (40 μL) | 200 μL |
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| AK5-USP33-20-GRGO | 20 (40 μL) | 200 μL |
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| AK5-USP33-20-GRGR | 20 (40 μL) | 200 μL |
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| AK5-USP33-20-GRAQ | 20 (40 μL) | 200 μL |
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| AK5-USP33-20-AQRE | 20 (40 μL) | 200 μL |
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| AK5-USP33-20-AQOR | 20 (40 μL) | 200 μL |
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| AK5-USP33-20-AQGO | 20 (40 μL) | 200 μL |
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| AK5-USP33-20-AQGR | 20 (40 μL) | 200 μL |
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| AK5-USP33-20-AQAQ | 20 (40 μL) | 200 μL |
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USP33 Gene Summary
This gene encodes a deubiquinating enzyme important in a variety of processes, including Slit-dependent cell migration and beta-2 adrenergic receptor signaling. The protein is negatively regulated through ubiquitination by von Hippel-Lindau tumor protein (VHL). Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jun 2012]
Gene Name: Ubiquitin Specific Peptidase 33
Chromosome: CHR1: 78161673 -78225537
Locus: 1p31.1
AK5 Gene Summary
This gene encodes a member of the adenylate kinase family, which is involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. This member is related to the UMP/CMP kinase of several species. It is located in the cytosol and expressed exclusively in brain. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Adenylate Kinase 5
Chromosome: CHR1: 77747661 -78025654
Locus: 1p31.1
Gene Diseases
The AK5 USP33 Fusion has been associated with the following diseases:
| Disease Name |
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| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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