AK3-DOCK8 Fusion FISH Probe
The AK3-DOCK8 Fusion FISH Probe is used to confirm a fusion of the AK3 and DOCK8 genes. The fusion of the AK3 and DOCK8 genes has been associated with Kidney Renal Clear Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| AK3-DOCK8-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| AK3-DOCK8-20-RERE | 20 (40 μL) | 200 μL |
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| AK3-DOCK8-20-REOR | 20 (40 μL) | 200 μL |
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| AK3-DOCK8-20-REGO | 20 (40 μL) | 200 μL |
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| AK3-DOCK8-20-REGR | 20 (40 μL) | 200 μL |
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| AK3-DOCK8-20-REAQ | 20 (40 μL) | 200 μL |
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| AK3-DOCK8-20-ORRE | 20 (40 μL) | 200 μL |
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| AK3-DOCK8-20-OROR | 20 (40 μL) | 200 μL |
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| AK3-DOCK8-20-ORGO | 20 (40 μL) | 200 μL |
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| AK3-DOCK8-20-ORAQ | 20 (40 μL) | 200 μL |
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| AK3-DOCK8-20-GORE | 20 (40 μL) | 200 μL |
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| AK3-DOCK8-20-GOOR | 20 (40 μL) | 200 μL |
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| AK3-DOCK8-20-GOGO | 20 (40 μL) | 200 μL |
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| AK3-DOCK8-20-GOGR | 20 (40 μL) | 200 μL |
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| AK3-DOCK8-20-GOAQ | 20 (40 μL) | 200 μL |
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| AK3-DOCK8-20-GRRE | 20 (40 μL) | 200 μL |
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| AK3-DOCK8-20-GROR | 20 (40 μL) | 200 μL |
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| AK3-DOCK8-20-GRGO | 20 (40 μL) | 200 μL |
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| AK3-DOCK8-20-GRGR | 20 (40 μL) | 200 μL |
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| AK3-DOCK8-20-GRAQ | 20 (40 μL) | 200 μL |
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| AK3-DOCK8-20-AQRE | 20 (40 μL) | 200 μL |
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| AK3-DOCK8-20-AQOR | 20 (40 μL) | 200 μL |
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| AK3-DOCK8-20-AQGO | 20 (40 μL) | 200 μL |
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| AK3-DOCK8-20-AQGR | 20 (40 μL) | 200 μL |
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| AK3-DOCK8-20-AQAQ | 20 (40 μL) | 200 μL |
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AK3 Gene Summary
The protein encoded by this gene is a GTP:ATP phosphotransferase that is found in the mitochondrial matrix. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Dec 2010]
Gene Name: Adenylate Kinase 3
Chromosome: CHR9: 4709556 -4742043
Locus: 9p24.1
DOCK8 Gene Summary
This gene encodes a member of the DOCK180 family of guanine nucleotide exchange factors. Guanine nucleotide exchange factors interact with Rho GTPases and are components of intracellular signaling networks. Mutations in this gene result in the autosomal recessive form of the hyper-IgE syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Jun 2010]
Gene Name: Dedicator Of Cytokinesis 8
Chromosome: CHR9: 214864 -465259
Locus: 9p24.3
Gene Diseases
The AK3 DOCK8 Fusion has been associated with the following diseases:
| Disease Name |
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| Kidney Renal Clear Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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