AJAP1-CYTH3 Fusion FISH Probe
The AJAP1-CYTH3 Fusion FISH Probe is used to confirm a fusion of the AJAP1 and CYTH3 genes. The fusion of the AJAP1 and CYTH3 genes has been associated with Adrenocortical Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| AJAP1-CYTH3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| AJAP1-CYTH3-20-RERE | 20 (40 μL) | 200 μL |
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| AJAP1-CYTH3-20-REOR | 20 (40 μL) | 200 μL |
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| AJAP1-CYTH3-20-REGO | 20 (40 μL) | 200 μL |
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| AJAP1-CYTH3-20-REGR | 20 (40 μL) | 200 μL |
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| AJAP1-CYTH3-20-REAQ | 20 (40 μL) | 200 μL |
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| AJAP1-CYTH3-20-ORRE | 20 (40 μL) | 200 μL |
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| AJAP1-CYTH3-20-OROR | 20 (40 μL) | 200 μL |
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| AJAP1-CYTH3-20-ORGO | 20 (40 μL) | 200 μL |
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| AJAP1-CYTH3-20-ORAQ | 20 (40 μL) | 200 μL |
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| AJAP1-CYTH3-20-GORE | 20 (40 μL) | 200 μL |
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| AJAP1-CYTH3-20-GOOR | 20 (40 μL) | 200 μL |
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| AJAP1-CYTH3-20-GOGO | 20 (40 μL) | 200 μL |
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| AJAP1-CYTH3-20-GOGR | 20 (40 μL) | 200 μL |
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| AJAP1-CYTH3-20-GOAQ | 20 (40 μL) | 200 μL |
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| AJAP1-CYTH3-20-GRRE | 20 (40 μL) | 200 μL |
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| AJAP1-CYTH3-20-GROR | 20 (40 μL) | 200 μL |
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| AJAP1-CYTH3-20-GRGO | 20 (40 μL) | 200 μL |
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| AJAP1-CYTH3-20-GRGR | 20 (40 μL) | 200 μL |
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| AJAP1-CYTH3-20-GRAQ | 20 (40 μL) | 200 μL |
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| AJAP1-CYTH3-20-AQRE | 20 (40 μL) | 200 μL |
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| AJAP1-CYTH3-20-AQOR | 20 (40 μL) | 200 μL |
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| AJAP1-CYTH3-20-AQGO | 20 (40 μL) | 200 μL |
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| AJAP1-CYTH3-20-AQGR | 20 (40 μL) | 200 μL |
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| AJAP1-CYTH3-20-AQAQ | 20 (40 μL) | 200 μL |
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CYTH3 Gene Summary
This gene encodes a member of the PSCD (pleckstrin homology, Sec7 and coiled-coil domains) family. PSCD family members have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This encoded protein is involved in the control of Golgi structure and function, and it may have a physiological role in regulating ADP-ribosylation factor protein 6 (ARF) functions, in addition to acting on ARF1. [provided by RefSeq, Jul 2008]
Gene Name: Cytohesin 3
Chromosome: CHR7: 6201411 -6312242
Locus: 7p22.1
AJAP1 Gene Summary
The Adherens Junctions Associated Protein 1 (AJAP1) gene is located on chr1 :4715104-4843851 at 1p36.32.
Gene Name: Adherens Junctions Associated Protein 1
Chromosome: CHR1: 4715104 -4843851
Locus: 1p36.32
Gene Diseases
The AJAP1 CYTH3 Fusion has been associated with the following diseases:
| Disease Name |
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| Adrenocortical Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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