AHR-TSPAN13 Fusion FISH Probe
The AHR-TSPAN13 Fusion FISH Probe is used to confirm a fusion of the AHR and TSPAN13 genes. The fusion of the AHR and TSPAN13 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| AHR-TSPAN13-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| AHR-TSPAN13-20-RERE | 20 (40 μL) | 200 μL |
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| AHR-TSPAN13-20-REOR | 20 (40 μL) | 200 μL |
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| AHR-TSPAN13-20-REGO | 20 (40 μL) | 200 μL |
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| AHR-TSPAN13-20-REGR | 20 (40 μL) | 200 μL |
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| AHR-TSPAN13-20-REAQ | 20 (40 μL) | 200 μL |
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| AHR-TSPAN13-20-ORRE | 20 (40 μL) | 200 μL |
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| AHR-TSPAN13-20-OROR | 20 (40 μL) | 200 μL |
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| AHR-TSPAN13-20-ORGO | 20 (40 μL) | 200 μL |
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| AHR-TSPAN13-20-ORAQ | 20 (40 μL) | 200 μL |
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| AHR-TSPAN13-20-GORE | 20 (40 μL) | 200 μL |
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| AHR-TSPAN13-20-GOOR | 20 (40 μL) | 200 μL |
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| AHR-TSPAN13-20-GOGO | 20 (40 μL) | 200 μL |
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| AHR-TSPAN13-20-GOGR | 20 (40 μL) | 200 μL |
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| AHR-TSPAN13-20-GOAQ | 20 (40 μL) | 200 μL |
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| AHR-TSPAN13-20-GRRE | 20 (40 μL) | 200 μL |
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| AHR-TSPAN13-20-GROR | 20 (40 μL) | 200 μL |
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| AHR-TSPAN13-20-GRGO | 20 (40 μL) | 200 μL |
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| AHR-TSPAN13-20-GRGR | 20 (40 μL) | 200 μL |
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| AHR-TSPAN13-20-GRAQ | 20 (40 μL) | 200 μL |
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| AHR-TSPAN13-20-AQRE | 20 (40 μL) | 200 μL |
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| AHR-TSPAN13-20-AQOR | 20 (40 μL) | 200 μL |
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| AHR-TSPAN13-20-AQGO | 20 (40 μL) | 200 μL |
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| AHR-TSPAN13-20-AQGR | 20 (40 μL) | 200 μL |
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| AHR-TSPAN13-20-AQAQ | 20 (40 μL) | 200 μL |
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AHR Gene Summary
The protein encoded by this gene is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm; upon ligand binding, this protein moves to the nucleus and stimulates transcription of target genes. [provided by RefSeq, Sep 2015]
Gene Name: Aryl Hydrocarbon Receptor
Chromosome: CHR7: 17338275 -17385775
Locus: 7p21.1
TSPAN13 Gene Summary
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. [provided by RefSeq, Jul 2008]
Gene Name: Tetraspanin 13
Chromosome: CHR7: 16793350 -16824161
Locus: 7p21.1
Gene Diseases
The AHR TSPAN13 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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