AHNAK-SUPT16H Fusion FISH Probe
The AHNAK-SUPT16H Fusion FISH Probe is used to confirm a fusion of the AHNAK and SUPT16H genes. The fusion of the AHNAK and SUPT16H genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| AHNAK-SUPT16H-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| AHNAK-SUPT16H-20-RERE | 20 (40 μL) | 200 μL |
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| AHNAK-SUPT16H-20-REOR | 20 (40 μL) | 200 μL |
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| AHNAK-SUPT16H-20-REGO | 20 (40 μL) | 200 μL |
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| AHNAK-SUPT16H-20-REGR | 20 (40 μL) | 200 μL |
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| AHNAK-SUPT16H-20-REAQ | 20 (40 μL) | 200 μL |
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| AHNAK-SUPT16H-20-ORRE | 20 (40 μL) | 200 μL |
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| AHNAK-SUPT16H-20-OROR | 20 (40 μL) | 200 μL |
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| AHNAK-SUPT16H-20-ORGO | 20 (40 μL) | 200 μL |
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| AHNAK-SUPT16H-20-ORAQ | 20 (40 μL) | 200 μL |
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| AHNAK-SUPT16H-20-GORE | 20 (40 μL) | 200 μL |
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| AHNAK-SUPT16H-20-GOOR | 20 (40 μL) | 200 μL |
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| AHNAK-SUPT16H-20-GOGO | 20 (40 μL) | 200 μL |
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| AHNAK-SUPT16H-20-GOGR | 20 (40 μL) | 200 μL |
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| AHNAK-SUPT16H-20-GOAQ | 20 (40 μL) | 200 μL |
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| AHNAK-SUPT16H-20-GRRE | 20 (40 μL) | 200 μL |
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| AHNAK-SUPT16H-20-GROR | 20 (40 μL) | 200 μL |
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| AHNAK-SUPT16H-20-GRGO | 20 (40 μL) | 200 μL |
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| AHNAK-SUPT16H-20-GRGR | 20 (40 μL) | 200 μL |
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| AHNAK-SUPT16H-20-GRAQ | 20 (40 μL) | 200 μL |
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| AHNAK-SUPT16H-20-AQRE | 20 (40 μL) | 200 μL |
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| AHNAK-SUPT16H-20-AQOR | 20 (40 μL) | 200 μL |
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| AHNAK-SUPT16H-20-AQGO | 20 (40 μL) | 200 μL |
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| AHNAK-SUPT16H-20-AQGR | 20 (40 μL) | 200 μL |
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| AHNAK-SUPT16H-20-AQAQ | 20 (40 μL) | 200 μL |
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SUPT16H Gene Summary
Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT (facilitates chromatin transcription), interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT is composed of an 80 kDa subunit and a 140 kDa subunit; this gene encodes the 140 kDa subunit. [provided by RefSeq, Feb 2009]
Gene Name: SPT16 Homolog, Facilitates Chromatin Remodeling Subunit
Chromosome: CHR14: 21819630 -21852425
Locus: 14q11.2
AHNAK Gene Summary
The protein encoded by this gene is a large (700 kDa) structural scaffold protein consisting of a central domain with 128 aa repeats. The encoded protein may play a role in such diverse processes as blood-brain barrier formation, cell structure and migration, cardiac calcium channel regulation, and tumor metastasis. A much shorter variant encoding a 17 kDa isoform exists for this gene, and the shorter isoform initiates a feedback loop that regulates alternative splicing of this gene. [provided by RefSeq, Oct 2016]
Gene Name: AHNAK Nucleoprotein
Chromosome: CHR11: 62201015 -62314332
Locus: 11q12.3
Gene Diseases
The AHNAK SUPT16H Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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