AHNAK-DPF2 Fusion FISH Probe
The AHNAK-DPF2 Fusion FISH Probe is used to confirm a fusion of the AHNAK and DPF2 genes. The fusion of the AHNAK and DPF2 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| AHNAK-DPF2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| AHNAK-DPF2-20-RERE | 20 (40 μL) | 200 μL |
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| AHNAK-DPF2-20-REOR | 20 (40 μL) | 200 μL |
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| AHNAK-DPF2-20-REGO | 20 (40 μL) | 200 μL |
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| AHNAK-DPF2-20-REGR | 20 (40 μL) | 200 μL |
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| AHNAK-DPF2-20-REAQ | 20 (40 μL) | 200 μL |
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| AHNAK-DPF2-20-ORRE | 20 (40 μL) | 200 μL |
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| AHNAK-DPF2-20-OROR | 20 (40 μL) | 200 μL |
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| AHNAK-DPF2-20-ORGO | 20 (40 μL) | 200 μL |
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| AHNAK-DPF2-20-ORAQ | 20 (40 μL) | 200 μL |
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| AHNAK-DPF2-20-GORE | 20 (40 μL) | 200 μL |
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| AHNAK-DPF2-20-GOOR | 20 (40 μL) | 200 μL |
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| AHNAK-DPF2-20-GOGO | 20 (40 μL) | 200 μL |
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| AHNAK-DPF2-20-GOGR | 20 (40 μL) | 200 μL |
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| AHNAK-DPF2-20-GOAQ | 20 (40 μL) | 200 μL |
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| AHNAK-DPF2-20-GRRE | 20 (40 μL) | 200 μL |
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| AHNAK-DPF2-20-GROR | 20 (40 μL) | 200 μL |
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| AHNAK-DPF2-20-GRGO | 20 (40 μL) | 200 μL |
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| AHNAK-DPF2-20-GRGR | 20 (40 μL) | 200 μL |
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| AHNAK-DPF2-20-GRAQ | 20 (40 μL) | 200 μL |
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| AHNAK-DPF2-20-AQRE | 20 (40 μL) | 200 μL |
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| AHNAK-DPF2-20-AQOR | 20 (40 μL) | 200 μL |
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| AHNAK-DPF2-20-AQGO | 20 (40 μL) | 200 μL |
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| AHNAK-DPF2-20-AQGR | 20 (40 μL) | 200 μL |
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| AHNAK-DPF2-20-AQAQ | 20 (40 μL) | 200 μL |
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DPF2 Gene Summary
The protein encoded by this gene is a member of the d4 domain family, characterized by a zinc finger-like structural motif. This protein functions as a transcription factor which is necessary for the apoptotic response following deprivation of survival factors. It likely serves a regulatory role in rapid hematopoietic cell growth and turnover. This gene is considered a candidate gene for multiple endocrine neoplasia type I, an inherited cancer syndrome involving multiple parathyroid, enteropancreatic, and pituitary tumors. [provided by RefSeq, Jul 2008]
Gene Name: Double PHD Fingers 2
Chromosome: CHR11: 65101224 -65120451
Locus: 11q13.1
AHNAK Gene Summary
The protein encoded by this gene is a large (700 kDa) structural scaffold protein consisting of a central domain with 128 aa repeats. The encoded protein may play a role in such diverse processes as blood-brain barrier formation, cell structure and migration, cardiac calcium channel regulation, and tumor metastasis. A much shorter variant encoding a 17 kDa isoform exists for this gene, and the shorter isoform initiates a feedback loop that regulates alternative splicing of this gene. [provided by RefSeq, Oct 2016]
Gene Name: AHNAK Nucleoprotein
Chromosome: CHR11: 62201015 -62314332
Locus: 11q12.3
Gene Diseases
The AHNAK DPF2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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