AHNAK-BIRC6 Fusion FISH Probe
The AHNAK-BIRC6 Fusion FISH Probe is used to confirm a fusion of the AHNAK and BIRC6 genes. The fusion of the AHNAK and BIRC6 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| AHNAK-BIRC6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| AHNAK-BIRC6-20-RERE | 20 (40 μL) | 200 μL |
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| AHNAK-BIRC6-20-REOR | 20 (40 μL) | 200 μL |
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| AHNAK-BIRC6-20-REGO | 20 (40 μL) | 200 μL |
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| AHNAK-BIRC6-20-REGR | 20 (40 μL) | 200 μL |
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| AHNAK-BIRC6-20-REAQ | 20 (40 μL) | 200 μL |
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| AHNAK-BIRC6-20-ORRE | 20 (40 μL) | 200 μL |
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| AHNAK-BIRC6-20-OROR | 20 (40 μL) | 200 μL |
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| AHNAK-BIRC6-20-ORGO | 20 (40 μL) | 200 μL |
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| AHNAK-BIRC6-20-ORAQ | 20 (40 μL) | 200 μL |
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| AHNAK-BIRC6-20-GORE | 20 (40 μL) | 200 μL |
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| AHNAK-BIRC6-20-GOOR | 20 (40 μL) | 200 μL |
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| AHNAK-BIRC6-20-GOGO | 20 (40 μL) | 200 μL |
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| AHNAK-BIRC6-20-GOGR | 20 (40 μL) | 200 μL |
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| AHNAK-BIRC6-20-GOAQ | 20 (40 μL) | 200 μL |
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| AHNAK-BIRC6-20-GRRE | 20 (40 μL) | 200 μL |
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| AHNAK-BIRC6-20-GROR | 20 (40 μL) | 200 μL |
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| AHNAK-BIRC6-20-GRGO | 20 (40 μL) | 200 μL |
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| AHNAK-BIRC6-20-GRGR | 20 (40 μL) | 200 μL |
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| AHNAK-BIRC6-20-GRAQ | 20 (40 μL) | 200 μL |
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| AHNAK-BIRC6-20-AQRE | 20 (40 μL) | 200 μL |
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| AHNAK-BIRC6-20-AQOR | 20 (40 μL) | 200 μL |
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| AHNAK-BIRC6-20-AQGO | 20 (40 μL) | 200 μL |
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| AHNAK-BIRC6-20-AQGR | 20 (40 μL) | 200 μL |
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| AHNAK-BIRC6-20-AQAQ | 20 (40 μL) | 200 μL |
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BIRC6 Gene Summary
This gene encodes a protein with a BIR (baculoviral inhibition of apoptosis protein repeat) domain and a UBCc (ubiquitin-conjugating enzyme E2, catalytic) domain. This protein inhibits apoptosis by facilitating the degradation of apoptotic proteins by ubiquitination. [provided by RefSeq, Jul 2008]
Gene Name: Baculoviral IAP Repeat Containing 6
Chromosome: CHR2: 32582095 -32843965
Locus: 2p22.3
AHNAK Gene Summary
The protein encoded by this gene is a large (700 kDa) structural scaffold protein consisting of a central domain with 128 aa repeats. The encoded protein may play a role in such diverse processes as blood-brain barrier formation, cell structure and migration, cardiac calcium channel regulation, and tumor metastasis. A much shorter variant encoding a 17 kDa isoform exists for this gene, and the shorter isoform initiates a feedback loop that regulates alternative splicing of this gene. [provided by RefSeq, Oct 2016]
Gene Name: AHNAK Nucleoprotein
Chromosome: CHR11: 62201015 -62314332
Locus: 11q12.3
Gene Diseases
The AHNAK BIRC6 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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