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AGRN-NOC4L Fusion FISH Probe

The AGRN-NOC4L Fusion FISH Probe is used to confirm a fusion of the AGRN and NOC4L genes. The fusion of the AGRN and NOC4L genes has been associated with Lung Squamous Cell Carcinoma, and Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
AGRN-NOC4L-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
AGRN-NOC4L-20-RERE 20 (40 μL) 200 μL
AGRN-NOC4L-20-REOR 20 (40 μL) 200 μL
AGRN-NOC4L-20-REGO 20 (40 μL) 200 μL
AGRN-NOC4L-20-REGR 20 (40 μL) 200 μL
AGRN-NOC4L-20-REAQ 20 (40 μL) 200 μL
AGRN-NOC4L-20-ORRE 20 (40 μL) 200 μL
AGRN-NOC4L-20-OROR 20 (40 μL) 200 μL
AGRN-NOC4L-20-ORGO 20 (40 μL) 200 μL
AGRN-NOC4L-20-ORAQ 20 (40 μL) 200 μL
AGRN-NOC4L-20-GORE 20 (40 μL) 200 μL
AGRN-NOC4L-20-GOOR 20 (40 μL) 200 μL
AGRN-NOC4L-20-GOGO 20 (40 μL) 200 μL
AGRN-NOC4L-20-GOGR 20 (40 μL) 200 μL
AGRN-NOC4L-20-GOAQ 20 (40 μL) 200 μL
AGRN-NOC4L-20-GRRE 20 (40 μL) 200 μL
AGRN-NOC4L-20-GROR 20 (40 μL) 200 μL
AGRN-NOC4L-20-GRGO 20 (40 μL) 200 μL
AGRN-NOC4L-20-GRGR 20 (40 μL) 200 μL
AGRN-NOC4L-20-GRAQ 20 (40 μL) 200 μL
AGRN-NOC4L-20-AQRE 20 (40 μL) 200 μL
AGRN-NOC4L-20-AQOR 20 (40 μL) 200 μL
AGRN-NOC4L-20-AQGO 20 (40 μL) 200 μL
AGRN-NOC4L-20-AQGR 20 (40 μL) 200 μL
AGRN-NOC4L-20-AQAQ 20 (40 μL) 200 μL

NOC4L Gene Summary

The Nucleolar Complex Associated 4 Homolog (NOC4L) gene is located on chr12 :132628992-132636986 at 12q24.33.

Gene Name: Nucleolar Complex Associated 4 Homolog

Chromosome: CHR12: 132628992 -132636986

Locus: 12q24.33

AGRN Gene Summary

This gene encodes one of several proteins that are critical in the development of the neuromuscular junction (NMJ), as identified in mouse knock-out studies. The encoded protein contains several laminin G, Kazal type serine protease inhibitor, and epidermal growth factor domains. Additional post-translational modifications occur to add glycosaminoglycans and disulfide bonds. In one family with congenital myasthenic syndrome affecting limb-girdle muscles, a mutation in this gene was found. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2015]

Gene Name: Agrin

Chromosome: CHR1: 955502 -991499

Locus: 1p36.33

Gene Diseases

The AGRN NOC4L Fusion has been associated with the following diseases:

Disease Name
Lung Squamous Cell Carcinoma
Breast Invasive Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.