AGR2-ANXA1 Fusion FISH Probe
The AGR2-ANXA1 Fusion FISH Probe is used to confirm a fusion of the AGR2 and ANXA1 genes. The fusion of the AGR2 and ANXA1 genes has been associated with Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| AGR2-ANXA1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| AGR2-ANXA1-20-RERE | 20 (40 μL) | 200 μL |
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| AGR2-ANXA1-20-REOR | 20 (40 μL) | 200 μL |
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| AGR2-ANXA1-20-REGO | 20 (40 μL) | 200 μL |
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| AGR2-ANXA1-20-REGR | 20 (40 μL) | 200 μL |
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| AGR2-ANXA1-20-REAQ | 20 (40 μL) | 200 μL |
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| AGR2-ANXA1-20-ORRE | 20 (40 μL) | 200 μL |
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| AGR2-ANXA1-20-OROR | 20 (40 μL) | 200 μL |
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| AGR2-ANXA1-20-ORGO | 20 (40 μL) | 200 μL |
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| AGR2-ANXA1-20-ORAQ | 20 (40 μL) | 200 μL |
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| AGR2-ANXA1-20-GORE | 20 (40 μL) | 200 μL |
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| AGR2-ANXA1-20-GOOR | 20 (40 μL) | 200 μL |
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| AGR2-ANXA1-20-GOGO | 20 (40 μL) | 200 μL |
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| AGR2-ANXA1-20-GOGR | 20 (40 μL) | 200 μL |
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| AGR2-ANXA1-20-GOAQ | 20 (40 μL) | 200 μL |
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| AGR2-ANXA1-20-GRRE | 20 (40 μL) | 200 μL |
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| AGR2-ANXA1-20-GROR | 20 (40 μL) | 200 μL |
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| AGR2-ANXA1-20-GRGO | 20 (40 μL) | 200 μL |
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| AGR2-ANXA1-20-GRGR | 20 (40 μL) | 200 μL |
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| AGR2-ANXA1-20-GRAQ | 20 (40 μL) | 200 μL |
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| AGR2-ANXA1-20-AQRE | 20 (40 μL) | 200 μL |
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| AGR2-ANXA1-20-AQOR | 20 (40 μL) | 200 μL |
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| AGR2-ANXA1-20-AQGO | 20 (40 μL) | 200 μL |
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| AGR2-ANXA1-20-AQGR | 20 (40 μL) | 200 μL |
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| AGR2-ANXA1-20-AQAQ | 20 (40 μL) | 200 μL |
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ANXA1 Gene Summary
This gene encodes a membrane-localized protein that binds phospholipids. This protein inhibits phospholipase A2 and has anti-inflammatory activity. Loss of function or expression of this gene has been detected in multiple tumors. [provided by RefSeq, Dec 2014]
Gene Name: Annexin A1
Chromosome: CHR9: 75766780 -75785307
Locus: 9q21.13
AGR2 Gene Summary
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This protein plays a role in cell migration, cellular transformation and metastasis and is as a p53 inhibitor. As an ER-localized molecular chaperone, it plays a role in the folding, trafficking, and assembly of cysteine-rich transmembrane receptors and the cysteine-rich intestinal gylcoprotein mucin. This gene has been implicated in inflammatory bowel disease and cancer progression. [provided by RefSeq, Mar 2017]
Gene Name: Anterior Gradient 2, Protein Disulphide Isomerase Family Member
Chromosome: CHR7: 16832263 -16844738
Locus: 7p21.1
Gene Diseases
The AGR2 ANXA1 Fusion has been associated with the following diseases:
| Disease Name |
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| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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